The effects of microwave radiation on rabbit's retina
Purpose: Mobile cell phones are used extensively these days, and their microwave (MW) radiation has been shown to affect the eye. The purpose of the present study was to evaluate the effects of MW radiation on rabbit retina. Methods: This experimental study (concluded in 2015) was conducted on 40 ad...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2018-03-01
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| Series: | Journal of Current Ophthalmology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2452232517300562 |
| _version_ | 1819276806886260736 |
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| author | Mohammad R. Talebnejad Ali Sadeghi-Sarvestani M. Hossein Nowroozzadeh Seyed Mohammad J. Mortazavi Abbas Alighanbari Mohammad R. Khalili |
| author_facet | Mohammad R. Talebnejad Ali Sadeghi-Sarvestani M. Hossein Nowroozzadeh Seyed Mohammad J. Mortazavi Abbas Alighanbari Mohammad R. Khalili |
| author_sort | Mohammad R. Talebnejad |
| collection | DOAJ |
| description | Purpose: Mobile cell phones are used extensively these days, and their microwave (MW) radiation has been shown to affect the eye. The purpose of the present study was to evaluate the effects of MW radiation on rabbit retina.
Methods: This experimental study (concluded in 2015) was conducted on 40 adult white New Zealand rabbits. A Global System for Mobile Communications (GSM) cell phone simulator was used for MW irradiation. The rabbits were randomized into five groups (8 in each) and treated as follows: Group 1: no irradiation (sham); Group 2: irradiation at 10 cm for 1 day; Group 3: irradiation at 30 cm for 1 day; Group 4: irradiation at 10 cm for 3 days; and Group 5: irradiation at 30 cm for 3 days. Scotopic and photopic electroretinography (ERG) responses were obtained at baseline and 7 days after the last exposure. Then all the rabbits were euthanized, and their eyes were enucleated and sent for pathology examination. Kruskal–Wallis and Chi-Square tests were used to evaluate intergroup differences in ERG parameters and histological findings, respectively.
Results: ERG responses obtained 7 days after irradiation did not show any statistically significant difference between the groups (P > 0.1, for all tested parameters). There were statistically non-significant trends toward greater changes in the MW irradiated eyes. In pathological examination, retina was normal with no sign of degeneration or infiltration. Ciliary body congestion was observed in greater fraction of those who received higher MW doses. (P = 0.005).
Conclusions: Histopathologically, cell phone simulated MW irradiation had no significant detrimental effect on the retina. However, ciliary body congestion was observed in greater fraction of those who received higher MW doses. Although there was no significant difference between post-treatment mean ERG values, there were statistically non-significant trends toward greater changes in the MW irradiated eyes. |
| first_indexed | 2024-12-23T23:46:05Z |
| format | Article |
| id | doaj.art-57890f72903f42a58194f521d2be33ed |
| institution | Directory Open Access Journal |
| issn | 2452-2325 |
| language | English |
| last_indexed | 2024-12-23T23:46:05Z |
| publishDate | 2018-03-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Current Ophthalmology |
| spelling | doaj.art-57890f72903f42a58194f521d2be33ed2022-12-21T17:25:31ZengWolters Kluwer Medknow PublicationsJournal of Current Ophthalmology2452-23252018-03-01301747910.1016/j.joco.2017.08.010The effects of microwave radiation on rabbit's retinaMohammad R. Talebnejad0Ali Sadeghi-Sarvestani1M. Hossein Nowroozzadeh2Seyed Mohammad J. Mortazavi3Abbas Alighanbari4Mohammad R. Khalili5Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IranPoostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IranPoostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IranThe Ionizing and Non-Ionizing Radiation Protection Research Center, Shiraz University of Medical Sciences, Shiraz, IranSchool of Electrical and Computer Engineering, Shiraz University, Shiraz, IranPoostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IranPurpose: Mobile cell phones are used extensively these days, and their microwave (MW) radiation has been shown to affect the eye. The purpose of the present study was to evaluate the effects of MW radiation on rabbit retina. Methods: This experimental study (concluded in 2015) was conducted on 40 adult white New Zealand rabbits. A Global System for Mobile Communications (GSM) cell phone simulator was used for MW irradiation. The rabbits were randomized into five groups (8 in each) and treated as follows: Group 1: no irradiation (sham); Group 2: irradiation at 10 cm for 1 day; Group 3: irradiation at 30 cm for 1 day; Group 4: irradiation at 10 cm for 3 days; and Group 5: irradiation at 30 cm for 3 days. Scotopic and photopic electroretinography (ERG) responses were obtained at baseline and 7 days after the last exposure. Then all the rabbits were euthanized, and their eyes were enucleated and sent for pathology examination. Kruskal–Wallis and Chi-Square tests were used to evaluate intergroup differences in ERG parameters and histological findings, respectively. Results: ERG responses obtained 7 days after irradiation did not show any statistically significant difference between the groups (P > 0.1, for all tested parameters). There were statistically non-significant trends toward greater changes in the MW irradiated eyes. In pathological examination, retina was normal with no sign of degeneration or infiltration. Ciliary body congestion was observed in greater fraction of those who received higher MW doses. (P = 0.005). Conclusions: Histopathologically, cell phone simulated MW irradiation had no significant detrimental effect on the retina. However, ciliary body congestion was observed in greater fraction of those who received higher MW doses. Although there was no significant difference between post-treatment mean ERG values, there were statistically non-significant trends toward greater changes in the MW irradiated eyes.http://www.sciencedirect.com/science/article/pii/S2452232517300562Ciliary bodyElectroretinographyIrradiationMicrowaveRetina |
| spellingShingle | Mohammad R. Talebnejad Ali Sadeghi-Sarvestani M. Hossein Nowroozzadeh Seyed Mohammad J. Mortazavi Abbas Alighanbari Mohammad R. Khalili The effects of microwave radiation on rabbit's retina Journal of Current Ophthalmology Ciliary body Electroretinography Irradiation Microwave Retina |
| title | The effects of microwave radiation on rabbit's retina |
| title_full | The effects of microwave radiation on rabbit's retina |
| title_fullStr | The effects of microwave radiation on rabbit's retina |
| title_full_unstemmed | The effects of microwave radiation on rabbit's retina |
| title_short | The effects of microwave radiation on rabbit's retina |
| title_sort | effects of microwave radiation on rabbit s retina |
| topic | Ciliary body Electroretinography Irradiation Microwave Retina |
| url | http://www.sciencedirect.com/science/article/pii/S2452232517300562 |
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