In vivo isotope tracing reveals the versatility of glucose as a brown adipose tissue substrate

In vivo isotope tracing reveals the versatility of glucose as a brown adipose tissue substrate

Summary: Active brown adipose tissue (BAT) consumes copious amounts of glucose, yet how glucose metabolism supports thermogenesis is unclear. By combining transcriptomics, metabolomics, and stable isotope tracing in vivo, we systematically analyze BAT glucose utilization in mice during acute and chr...

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Bibliographic Details
Main Authors: Su Myung Jung, Will G. Doxsey, Johnny Le, John A. Haley, Lorena Mazuecos, Amelia K. Luciano, Huawei Li, Cholsoon Jang, David A. Guertin
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Cell Reports
Subjects:
brown fat
brown adipose tissue
BAT
brown adipocyte
metabolomics
stable isotope tracing
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721008822

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