Loureirin B Inhibits Hypertrophic Scar Formation via Inhibition of the TGF-β1-ERK/JNK Pathway

Loureirin B Inhibits Hypertrophic Scar Formation via Inhibition of the TGF-β1-ERK/JNK Pathway

Background/Aims: Our previous study confirmed that Loureirin B (LB) can inhibit hypertrophic scar formation. However, the mechanism of LB-mediated inhibition of scar formation is still unknown. Methods: Immunohistochemistry was used to detect expression of Col1, FN and TGF-β1 in skin and scar tissue...

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Bibliographic Details
Main Authors: Ting He, Xiaozhi Bai, Longlong Yang, Lei Fan, Yan Li, Linlin Su, Jianxin Gao, Shichao Han, Dahai Hu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Extracellular Matrix
Loureirin B
Hypertrophic Scar
Fibroblasts
MAPK Pathway
Online Access:http://www.karger.com/Article/FullText/430385

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