Praziquantel treatment after Schistosoma japonicum infection maintains hepatic insulin sensitivity and improves glucose metabolism in mice

Praziquantel treatment after Schistosoma japonicum infection maintains hepatic insulin sensitivity and improves glucose metabolism in mice

Abstract Background Epidemiological studies in China have revealed that Schistosoma japonicum infection is inversely correlated with metabolic syndrome, even after repeated chemotherapy with praziquantel (PZQ). We investigated the effect of chronic S. japonicum infection, PZQ chemotherapy, and solub...

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Bibliographic Details
Main Authors: Xiaofeng Luo, Yuxiao Zhu, Ran Liu, Jingwei Song, Fan Zhang, Wenyue Zhang, Zhipeng Xu, Min Hou, Bingya Yang, Lin Chen, Minjun Ji
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Parasites & Vectors
Subjects:
Schistosoma japonicum
Glucose metabolism
Insulin resistance
Anti-inflammatory cytokines
Online Access:http://link.springer.com/article/10.1186/s13071-017-2400-5

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