In vitro evaluation of 2-pyrazoline derivatives as DPP-4 inhibitors
In this study, the synthesis of three pyrazoline derivatives and the evaluation of their inhibitory effects on dipeptidyl peptidase (DPP-4) were aimed.
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2022-11-01
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| Series: | Türk Biyokimya Dergisi |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/tjb-2022-0161 |
| _version_ | 1797848438687137792 |
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| author | Temel Halide Edip Altıntop Mehlika Dilek Sever Belgin Özdemir Ahmet Akalın Çiftçi Gülşen |
| author_facet | Temel Halide Edip Altıntop Mehlika Dilek Sever Belgin Özdemir Ahmet Akalın Çiftçi Gülşen |
| author_sort | Temel Halide Edip |
| collection | DOAJ |
| description | In this study, the synthesis of three pyrazoline derivatives and the evaluation of their inhibitory effects on dipeptidyl peptidase (DPP-4) were aimed. |
| first_indexed | 2024-04-09T18:28:38Z |
| format | Article |
| id | doaj.art-5797907e44084af6b3acebabecc72b3d |
| institution | Directory Open Access Journal |
| issn | 1303-829X |
| language | English |
| last_indexed | 2024-04-09T18:28:38Z |
| publishDate | 2022-11-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Türk Biyokimya Dergisi |
| spelling | doaj.art-5797907e44084af6b3acebabecc72b3d2023-04-11T17:42:48ZengDe GruyterTürk Biyokimya Dergisi1303-829X2022-11-0148110410910.1515/tjb-2022-0161In vitro evaluation of 2-pyrazoline derivatives as DPP-4 inhibitorsTemel Halide Edip0Altıntop Mehlika Dilek1Sever Belgin2Özdemir Ahmet3Akalın Çiftçi Gülşen4Department of Biochemistry, Faculty of Pharmacy, Anadolu University,Eskişehir, TürkiyeDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University,Eskişehir, TürkiyeDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University,Eskişehir, TürkiyeDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University,Eskişehir, TürkiyeDepartment of Biochemistry, Faculty of Pharmacy, Anadolu University,Eskişehir, TürkiyeIn this study, the synthesis of three pyrazoline derivatives and the evaluation of their inhibitory effects on dipeptidyl peptidase (DPP-4) were aimed.https://doi.org/10.1515/tjb-2022-0161cytotoxicitydiabetes mellitusdipeptidyl peptidase-4molecular dockingpyrazoline |
| spellingShingle | Temel Halide Edip Altıntop Mehlika Dilek Sever Belgin Özdemir Ahmet Akalın Çiftçi Gülşen In vitro evaluation of 2-pyrazoline derivatives as DPP-4 inhibitors Türk Biyokimya Dergisi cytotoxicity diabetes mellitus dipeptidyl peptidase-4 molecular docking pyrazoline |
| title | In vitro evaluation of 2-pyrazoline derivatives as DPP-4 inhibitors |
| title_full | In vitro evaluation of 2-pyrazoline derivatives as DPP-4 inhibitors |
| title_fullStr | In vitro evaluation of 2-pyrazoline derivatives as DPP-4 inhibitors |
| title_full_unstemmed | In vitro evaluation of 2-pyrazoline derivatives as DPP-4 inhibitors |
| title_short | In vitro evaluation of 2-pyrazoline derivatives as DPP-4 inhibitors |
| title_sort | in vitro evaluation of 2 pyrazoline derivatives as dpp 4 inhibitors |
| topic | cytotoxicity diabetes mellitus dipeptidyl peptidase-4 molecular docking pyrazoline |
| url | https://doi.org/10.1515/tjb-2022-0161 |
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