Proteomic and metabolomic analyses reveal the novel targets of spermine for alleviating diabetic cardiomyopathy in type II diabetic mice

Proteomic and metabolomic analyses reveal the novel targets of spermine for alleviating diabetic cardiomyopathy in type II diabetic mice

Diabetic cardiomyopathy (DCM) is one of the most serious complications of diabetes. Recent cardiology studies suggest that spermine has a cardioprotective effect. Here, we used proteomic and metabolomic analyses to reveal the underlying research targets in a type II diabetic (T2D) mouse model treate...

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Bibliographic Details
Main Authors: Jian Sun, Jiyu Xu, Yong Liu, Xiaoyi Xu, Shumin Zhang, Yankun Hao, Yitong Lin, Yue Han, Feiya Li, Hui Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
diabetic cardiomyopathy
spermine
proteomic analysis
bioinformatic
PRKG1
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.1022861/full

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