Downregulation of LncRNA GCLC-1 Promotes Microcystin-LR-Induced Malignant Transformation of Human Liver Cells by Regulating GCLC Expression

Downregulation of LncRNA GCLC-1 Promotes Microcystin-LR-Induced Malignant Transformation of Human Liver Cells by Regulating GCLC Expression

Microcystin-LR (MCLR) is an aquatic toxin, which could lead to the development of hepatocellular carcinoma (HCC). Long non-coding RNAs (lncRNAs) are considered important regulatory elements in the occurrence and development of cancer. However, the roles and mechanisms of lncRNAs during the process o...

Full description

Bibliographic Details
Main Authors: Xinglei Huang, Zhaohui Su, Jiangheng Li, Junquan He, Na Zhao, Liyun Nie, Bin Guan, Qiuyue Huang, Huiliu Zhao, Guo-Dong Lu, Qingqing Nong
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Toxics
Subjects:
microcystin-LR
lncRNA GCLC-1
GCLC
carcinogenesis
Online Access:https://www.mdpi.com/2305-6304/11/2/162

Similar Items

Similar Items