Advances in the pathogenesis of Rett syndrome using cell models

Advances in the pathogenesis of Rett syndrome using cell models

Abstract Rett syndrome (RTT) is a progressive neurodevelopmental disorder that occurs mainly in girls with a range of typical symptoms of autism spectrum disorders. MeCP2 protein loss‐of‐function in neural lineage cells is the main cause of RTT pathogenicity. As it is still hard to understand the me...

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Bibliographic Details
Main Authors: Sijia Lu, Yongchang Chen, Zhengbo Wang
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:Animal Models and Experimental Medicine
Subjects:
cell models
MeCP2
pathogenesis
Rett syndrome
Online Access:https://doi.org/10.1002/ame2.12236

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