Evaluating Human T-Cell Therapy of Cytomegalovirus Organ Disease in HLA-Transgenic Mice.

Evaluating Human T-Cell Therapy of Cytomegalovirus Organ Disease in HLA-Transgenic Mice.

Reactivation of human cytomegalovirus (HCMV) can cause severe disease in recipients of hematopoietic stem cell transplantation. Although preclinical research in murine models as well as clinical trials have provided 'proof of concept' for infection control by pre-emptive CD8 T-cell immunot...

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Bibliographic Details
Main Authors: Simone Thomas, Sebastian Klobuch, Jürgen Podlech, Bodo Plachter, Petra Hoffmann, Angelique Renzaho, Matthias Theobald, Matthias J Reddehase, Wolfgang Herr, Niels A W Lemmermann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4504510?pdf=render

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