Ebselen Interferes with Alzheimer’s Disease by Regulating Mitochondrial Function
(1) Background: With unknown causes and no effective treatment available, Alzheimer’s disease (AD) places enormous pressure on families and society. Our previous study had shown that Ebselen at a high concentration (10.94 μM) improved the cognition of triple-transgenic AD (3×Tg-AD) mice and alleviat...
Main Authors: | Xuexia Li, Qingqing Shi, Hao Xu, Yufang Xiong, Chao Wang, Linfeng Le, Junliang Lian, Guoli Wu, Feiyuan Peng, Qiong Liu, Xiubo Du |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-07-01
|
Series: | Antioxidants |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3921/11/7/1350 |
Similar Items
-
Convergent Synthesis of Two Fluorescent Ebselen-Coumarin Heterodimers
by: Jim Küppers, et al.
Published: (2016-07-01) -
Melatonin and MitoEbselen-2 Are Radioprotective Agents to Mitochondria
by: Tsutomu Shimura, et al.
Published: (2022-12-01) -
The Potential Use of Ebselen in Treatment-Resistant Depression
by: Fitri Fareez Ramli, et al.
Published: (2022-04-01) -
Metallocenyl derivatives of ebselen are selective and competitive inhibitors of thioredoxin reductase
by: Koh, Wei Xiang, et al.
Published: (2022) -
Developing selective histone deacetylases (HDACs) inhibitors through ebselen and analogs
by: Wang Y, et al.
Published: (2017-05-01)