Hemolytic Uremic Syndrome: A Case Report

Thrombotic microangiopathy is a pathological condition comprised of microvascular thrombosis involving any body organ leading to thrombocytopenia, coombs-negative hemolytic anemia, and end-organ damage. The clinical presentation of the case shows typical hemolytic uremic syndrome, however, lab repo...

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Main Authors: Sandesh Gaire, Mandira Shrestha, Chaitanya Darshan Bhattarai, Susajjan Dhungana, Surakshya Gyawali, Arun Bajgain
Format: Article
Language:English
Published: Nepal Medical Association 2023-05-01
Series:Journal of Nepal Medical Association
Subjects:
Online Access:http://jnma.com.np/jnma/index.php/jnma/article/view/8151
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author Sandesh Gaire
Mandira Shrestha
Chaitanya Darshan Bhattarai
Susajjan Dhungana
Surakshya Gyawali
Arun Bajgain
author_facet Sandesh Gaire
Mandira Shrestha
Chaitanya Darshan Bhattarai
Susajjan Dhungana
Surakshya Gyawali
Arun Bajgain
author_sort Sandesh Gaire
collection DOAJ
description Thrombotic microangiopathy is a pathological condition comprised of microvascular thrombosis involving any body organ leading to thrombocytopenia, coombs-negative hemolytic anemia, and end-organ damage. The clinical presentation of the case shows typical hemolytic uremic syndrome, however, lab reports show atypical hemolytic uremic syndrome (low C3). Pain abdomen and loose stool with some signs of dehydration were initial presentations. Early initiation of renal replacement therapy and management of dehydration was done. Simple diarrhea can also manifest as acute kidney injury with the hemolytic uremic syndrome. Hence we should keep hemolytic uremic syndrome as the differential diagnosis of diarrhea. Irrespective of lab parameters, early management in line with the typical hemolytic uremic syndrome should be done for better outcomes.
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spelling doaj.art-57a71f7b1d1e46c0800819fd8d8712ef2023-05-22T10:54:38ZengNepal Medical AssociationJournal of Nepal Medical Association0028-27151815-672X2023-05-016126110.31729/jnma.8151Hemolytic Uremic Syndrome: A Case ReportSandesh Gaire0Mandira Shrestha1 Chaitanya Darshan Bhattarai2Susajjan Dhungana3Surakshya Gyawali4Arun Bajgain5Nepal Medical College and Teaching Hospital, Jorpati, Kathmandu, NepalDepartment of Paediatrics, Nepal Medical College and Teaching Hospital, Jorpati, Kathmandu, NepalNepal Medical College and Teaching Hospital, Jorpati, Kathmandu, NepalNepal Medical College and Teaching Hospital, Jorpati, Kathmandu, NepalNepal Medical College and Teaching Hospital, Jorpati, Kathmandu, NepalNepal Medical College and Teaching Hospital, Jorpati, Kathmandu, Nepal Thrombotic microangiopathy is a pathological condition comprised of microvascular thrombosis involving any body organ leading to thrombocytopenia, coombs-negative hemolytic anemia, and end-organ damage. The clinical presentation of the case shows typical hemolytic uremic syndrome, however, lab reports show atypical hemolytic uremic syndrome (low C3). Pain abdomen and loose stool with some signs of dehydration were initial presentations. Early initiation of renal replacement therapy and management of dehydration was done. Simple diarrhea can also manifest as acute kidney injury with the hemolytic uremic syndrome. Hence we should keep hemolytic uremic syndrome as the differential diagnosis of diarrhea. Irrespective of lab parameters, early management in line with the typical hemolytic uremic syndrome should be done for better outcomes. http://jnma.com.np/jnma/index.php/jnma/article/view/8151anemia; case reports; dehydration; renal replacement therapy.
spellingShingle Sandesh Gaire
Mandira Shrestha
Chaitanya Darshan Bhattarai
Susajjan Dhungana
Surakshya Gyawali
Arun Bajgain
Hemolytic Uremic Syndrome: A Case Report
Journal of Nepal Medical Association
anemia; case reports; dehydration; renal replacement therapy.
title Hemolytic Uremic Syndrome: A Case Report
title_full Hemolytic Uremic Syndrome: A Case Report
title_fullStr Hemolytic Uremic Syndrome: A Case Report
title_full_unstemmed Hemolytic Uremic Syndrome: A Case Report
title_short Hemolytic Uremic Syndrome: A Case Report
title_sort hemolytic uremic syndrome a case report
topic anemia; case reports; dehydration; renal replacement therapy.
url http://jnma.com.np/jnma/index.php/jnma/article/view/8151
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AT chaitanyadarshanbhattarai hemolyticuremicsyndromeacasereport
AT susajjandhungana hemolyticuremicsyndromeacasereport
AT surakshyagyawali hemolyticuremicsyndromeacasereport
AT arunbajgain hemolyticuremicsyndromeacasereport