Feasibility and utility of MRI and dynamic 18F-FDG-PET in an orthotopic organoid-based patient-derived mouse model of endometrial cancer

Feasibility and utility of MRI and dynamic 18F-FDG-PET in an orthotopic organoid-based patient-derived mouse model of endometrial cancer

Abstract Background Pelvic magnetic resonance imaging (MRI) and whole-body positron emission tomography-computed tomography (PET-CT) play an important role at primary diagnostic work-up and in detecting recurrent disease in endometrial cancer (EC) patients, however the preclinical use of these imagi...

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Bibliographic Details
Main Authors: Heidi Espedal, Hege F. Berg, Tina Fonnes, Kristine E. Fasmer, Camilla Krakstad, Ingfrid S. Haldorsen
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Translational Medicine
Subjects:
Preclinical imaging
Endometrial cancer
Organoid-PDX models
Dynamic PET
Translational imaging
Multimodal imaging
Online Access:https://doi.org/10.1186/s12967-021-03086-9

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