Estimating population norms for the health-related quality of life of adults in southern Jiangsu Province, China

Abstract Although national health-related quality of life population norms had been published based on the EuroQol 5-Dimensions 5-levels scale, China is a vast country with diverse cultural and social development in various regions. Therefore, regional population norms may better reflect the health...

Full description

Bibliographic Details
Main Authors: Wei Hu, Liang Zhou, Jiadong Chu, Na Sun, Xuanli Chen, Siyuan Liu, Yueping Shen
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-13910-x
_version_ 1818205302980345856
author Wei Hu
Liang Zhou
Jiadong Chu
Na Sun
Xuanli Chen
Siyuan Liu
Yueping Shen
author_facet Wei Hu
Liang Zhou
Jiadong Chu
Na Sun
Xuanli Chen
Siyuan Liu
Yueping Shen
author_sort Wei Hu
collection DOAJ
description Abstract Although national health-related quality of life population norms had been published based on the EuroQol 5-Dimensions 5-levels scale, China is a vast country with diverse cultural and social development in various regions. Therefore, regional population norms may better reflect the health status of residents in a given area. The purpose of the study was to derive the HRQoL population norm for adult general population in southern Jiangsu Province using the EQ-5D-5L scale and explore potential influencing factors. The data were based on a cross-sectional survey conducted in Liyang City from March 2019 to July 2020. EQ-5D-5L utility scores based on Chinese value set and EQ-VAS scores were used to assess HRQoL. The Tobit regression model and generalized linear model were performed to identify the association among potential covariates and HRQoL. The means (95% confidence interval) of the EQ-5D-5L utility scores and EQ-VAS scores were 0.981(0.980–0.983) and 83.6(83.2–83.9), respectively. Younger people (≤ 40 years old) were more likely to experience problems with anxiety or depression. Additionally, women had lower HRQoL scores although multivariate analysis found no statistical difference between the sexes. Lower HRQoL was associated with advanced age, lower socioeconomic status, no spouse, lack of regular physical activities, smoking cessation, and chronic non-communicable diseases. Subjects who declared that they were afflicted by diseases presented significantly lower utility scores, ranging from 0.823 (0.766–0.880) for memory-related diseases to 0.978 (0.967–0.989) for hepatic diseases. Regional population norms of HRQoL are needed in the health economic study owing to the great socioeconomic differences across regions in China. The present study provides HRQoL population norms for adults in southern Jiangsu. These norm values could help policy makers better allocate limited health resources and prioritize service plans.
first_indexed 2024-12-12T03:54:59Z
format Article
id doaj.art-57ad0e63feae42178a888834e810a458
institution Directory Open Access Journal
issn 2045-2322
language English
last_indexed 2024-12-12T03:54:59Z
publishDate 2022-06-01
publisher Nature Portfolio
record_format Article
series Scientific Reports
spelling doaj.art-57ad0e63feae42178a888834e810a4582022-12-22T00:39:16ZengNature PortfolioScientific Reports2045-23222022-06-0112111110.1038/s41598-022-13910-xEstimating population norms for the health-related quality of life of adults in southern Jiangsu Province, ChinaWei Hu0Liang Zhou1Jiadong Chu2Na Sun3Xuanli Chen4Siyuan Liu5Yueping Shen6Department of Epidemiology and Biostatistics, School of Public Health, Medical College of Soochow UniversityLiyang Center for Disease Control and PreventionDepartment of Epidemiology and Biostatistics, School of Public Health, Medical College of Soochow UniversityDepartment of Epidemiology and Biostatistics, School of Public Health, Medical College of Soochow UniversityDepartment of Epidemiology and Biostatistics, School of Public Health, Medical College of Soochow UniversityDepartment of Epidemiology and Biostatistics, School of Public Health, Medical College of Soochow UniversityDepartment of Epidemiology and Biostatistics, School of Public Health, Medical College of Soochow UniversityAbstract Although national health-related quality of life population norms had been published based on the EuroQol 5-Dimensions 5-levels scale, China is a vast country with diverse cultural and social development in various regions. Therefore, regional population norms may better reflect the health status of residents in a given area. The purpose of the study was to derive the HRQoL population norm for adult general population in southern Jiangsu Province using the EQ-5D-5L scale and explore potential influencing factors. The data were based on a cross-sectional survey conducted in Liyang City from March 2019 to July 2020. EQ-5D-5L utility scores based on Chinese value set and EQ-VAS scores were used to assess HRQoL. The Tobit regression model and generalized linear model were performed to identify the association among potential covariates and HRQoL. The means (95% confidence interval) of the EQ-5D-5L utility scores and EQ-VAS scores were 0.981(0.980–0.983) and 83.6(83.2–83.9), respectively. Younger people (≤ 40 years old) were more likely to experience problems with anxiety or depression. Additionally, women had lower HRQoL scores although multivariate analysis found no statistical difference between the sexes. Lower HRQoL was associated with advanced age, lower socioeconomic status, no spouse, lack of regular physical activities, smoking cessation, and chronic non-communicable diseases. Subjects who declared that they were afflicted by diseases presented significantly lower utility scores, ranging from 0.823 (0.766–0.880) for memory-related diseases to 0.978 (0.967–0.989) for hepatic diseases. Regional population norms of HRQoL are needed in the health economic study owing to the great socioeconomic differences across regions in China. The present study provides HRQoL population norms for adults in southern Jiangsu. These norm values could help policy makers better allocate limited health resources and prioritize service plans.https://doi.org/10.1038/s41598-022-13910-x
spellingShingle Wei Hu
Liang Zhou
Jiadong Chu
Na Sun
Xuanli Chen
Siyuan Liu
Yueping Shen
Estimating population norms for the health-related quality of life of adults in southern Jiangsu Province, China
Scientific Reports
title Estimating population norms for the health-related quality of life of adults in southern Jiangsu Province, China
title_full Estimating population norms for the health-related quality of life of adults in southern Jiangsu Province, China
title_fullStr Estimating population norms for the health-related quality of life of adults in southern Jiangsu Province, China
title_full_unstemmed Estimating population norms for the health-related quality of life of adults in southern Jiangsu Province, China
title_short Estimating population norms for the health-related quality of life of adults in southern Jiangsu Province, China
title_sort estimating population norms for the health related quality of life of adults in southern jiangsu province china
url https://doi.org/10.1038/s41598-022-13910-x
work_keys_str_mv AT weihu estimatingpopulationnormsforthehealthrelatedqualityoflifeofadultsinsouthernjiangsuprovincechina
AT liangzhou estimatingpopulationnormsforthehealthrelatedqualityoflifeofadultsinsouthernjiangsuprovincechina
AT jiadongchu estimatingpopulationnormsforthehealthrelatedqualityoflifeofadultsinsouthernjiangsuprovincechina
AT nasun estimatingpopulationnormsforthehealthrelatedqualityoflifeofadultsinsouthernjiangsuprovincechina
AT xuanlichen estimatingpopulationnormsforthehealthrelatedqualityoflifeofadultsinsouthernjiangsuprovincechina
AT siyuanliu estimatingpopulationnormsforthehealthrelatedqualityoflifeofadultsinsouthernjiangsuprovincechina
AT yuepingshen estimatingpopulationnormsforthehealthrelatedqualityoflifeofadultsinsouthernjiangsuprovincechina