Catheter-related Bloodstream Infection Rates, Distribution Of Infective Agents and Antibiotic Susceptibilities In Intensive Care Units: Results Of a 5.5-Year-Study
Introduction: Catheter-related infections and resistance to antimicrobials represent challenge in care units especially designed for high risk patients. Central venous catheter-related bloodstream infections due to multidrug resistant gram negative bacteria (CVC-r BSI) tend to increase. We aimed to...
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Format: | Article |
Language: | English |
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Bilimsel Tip Yayinevi
2015-03-01
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Series: | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
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Online Access: | http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2015-20-01-022-029.pdf |
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author | Aynur ATİLLA Zahide DOĞANAY Hale KEFELİ ÇELİK Süleyman Sırrı KILIÇ |
author_facet | Aynur ATİLLA Zahide DOĞANAY Hale KEFELİ ÇELİK Süleyman Sırrı KILIÇ |
author_sort | Aynur ATİLLA |
collection | DOAJ |
description | Introduction: Catheter-related infections and resistance to antimicrobials represent challenge in care units especially designed for high risk patients. Central venous catheter-related bloodstream infections due to multidrug resistant gram negative bacteria (CVC-r BSI) tend to increase. We aimed to investigate bloodstream infections rate related to central venous catheter, detect pathogens and antibiotic sensitivity status in our Intensive Care Units (ICU).
Materials and Methods: This study included patients with CVC-r BSI in our ICUs between January 2008 and July 2013. Records of
Infection Control Committee and patient fi les were retrospectively reviewed.
Results: CVC-r BSI rate was 2-8 per 1000 catheter days in ICUs between 2008-2013. We detected a total of 172 isolates in 166 CVC-r BSI. Of all isolates, 52% were gram negative, 27% gram positive and 21% Candida spp. ESBL was found 54.5% in Klebsiellae pneumoniae, and only one isolate demonstrated carbapenem resistance (4.2%). Carbapenem resistance was 91% in Acinetobacter baumannii. Methycillin-resistant Staphylococcus aureus (MRSA) was detected as %66.7, Methycillin-resistant coagulase-negative staphylococcus (MR-KNS) 100%, and Vancomycin-resistant Enterococcus spp. 9.5%.
Conclusion: Empirical therapy should be selected according to pathogens and their sensitivity results in ICUs reporting gram-negative microorganisms and higher resistance rates. |
first_indexed | 2024-04-10T14:57:32Z |
format | Article |
id | doaj.art-57b0bd47a51447d8832001280a9a3f37 |
institution | Directory Open Access Journal |
issn | 1300-932X 1300-932X |
language | English |
last_indexed | 2024-04-10T14:57:32Z |
publishDate | 2015-03-01 |
publisher | Bilimsel Tip Yayinevi |
record_format | Article |
series | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
spelling | doaj.art-57b0bd47a51447d8832001280a9a3f372023-02-15T16:07:15ZengBilimsel Tip YayineviFlora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi1300-932X1300-932X2015-03-012012229Catheter-related Bloodstream Infection Rates, Distribution Of Infective Agents and Antibiotic Susceptibilities In Intensive Care Units: Results Of a 5.5-Year-StudyAynur ATİLLA0Zahide DOĞANAY1Hale KEFELİ ÇELİK2Süleyman Sırrı KILIÇ3Clinic of Infectious Diseases and Clinical Microbiology, Samsun Training and Research Hospital, Samsun, TurkeyClinic of Anesthesiology and Reanimation, Samsun Training and Research Hospital, Samsun, TurkeyClinic of Anesthesiology and Reanimation, Samsun Training and Research Hospital, Samsun, TurkeyClinic of Infectious Diseases and Clinical Microbiology, Samsun Training and Research Hospital, Samsun, TurkeyIntroduction: Catheter-related infections and resistance to antimicrobials represent challenge in care units especially designed for high risk patients. Central venous catheter-related bloodstream infections due to multidrug resistant gram negative bacteria (CVC-r BSI) tend to increase. We aimed to investigate bloodstream infections rate related to central venous catheter, detect pathogens and antibiotic sensitivity status in our Intensive Care Units (ICU). Materials and Methods: This study included patients with CVC-r BSI in our ICUs between January 2008 and July 2013. Records of Infection Control Committee and patient fi les were retrospectively reviewed. Results: CVC-r BSI rate was 2-8 per 1000 catheter days in ICUs between 2008-2013. We detected a total of 172 isolates in 166 CVC-r BSI. Of all isolates, 52% were gram negative, 27% gram positive and 21% Candida spp. ESBL was found 54.5% in Klebsiellae pneumoniae, and only one isolate demonstrated carbapenem resistance (4.2%). Carbapenem resistance was 91% in Acinetobacter baumannii. Methycillin-resistant Staphylococcus aureus (MRSA) was detected as %66.7, Methycillin-resistant coagulase-negative staphylococcus (MR-KNS) 100%, and Vancomycin-resistant Enterococcus spp. 9.5%. Conclusion: Empirical therapy should be selected according to pathogens and their sensitivity results in ICUs reporting gram-negative microorganisms and higher resistance rates.http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2015-20-01-022-029.pdfCatheterBloodstream infectionResistantIntensive care units |
spellingShingle | Aynur ATİLLA Zahide DOĞANAY Hale KEFELİ ÇELİK Süleyman Sırrı KILIÇ Catheter-related Bloodstream Infection Rates, Distribution Of Infective Agents and Antibiotic Susceptibilities In Intensive Care Units: Results Of a 5.5-Year-Study Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi Catheter Bloodstream infection Resistant Intensive care units |
title | Catheter-related Bloodstream Infection Rates, Distribution Of Infective Agents and Antibiotic Susceptibilities In Intensive Care Units: Results Of a 5.5-Year-Study |
title_full | Catheter-related Bloodstream Infection Rates, Distribution Of Infective Agents and Antibiotic Susceptibilities In Intensive Care Units: Results Of a 5.5-Year-Study |
title_fullStr | Catheter-related Bloodstream Infection Rates, Distribution Of Infective Agents and Antibiotic Susceptibilities In Intensive Care Units: Results Of a 5.5-Year-Study |
title_full_unstemmed | Catheter-related Bloodstream Infection Rates, Distribution Of Infective Agents and Antibiotic Susceptibilities In Intensive Care Units: Results Of a 5.5-Year-Study |
title_short | Catheter-related Bloodstream Infection Rates, Distribution Of Infective Agents and Antibiotic Susceptibilities In Intensive Care Units: Results Of a 5.5-Year-Study |
title_sort | catheter related bloodstream infection rates distribution of infective agents and antibiotic susceptibilities in intensive care units results of a 5 5 year study |
topic | Catheter Bloodstream infection Resistant Intensive care units |
url | http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2015-20-01-022-029.pdf |
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