Application of Nanotechnology in Therapeutic Cancer Vaccines

Cancer vaccines stimulate the immune system within the body by introducing tumor antigens in various forms, such as tumor cells, tumor‐related proteins or peptides, and genes expressing tumor antigens, into the body. This activation of the immune response aims to prevent or treat tumors. Preventive...

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Main Authors: Jianmei Guo, Lin Tang, Kelin Li, Qingxin Ma, Shuda Luo, Ruoyu Cheng, Chaoyong Liu
Format: Article
Language:English
Published: Wiley-VCH 2023-07-01
Series:Advanced NanoBiomed Research
Subjects:
Online Access:https://doi.org/10.1002/anbr.202200122
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author Jianmei Guo
Lin Tang
Kelin Li
Qingxin Ma
Shuda Luo
Ruoyu Cheng
Chaoyong Liu
author_facet Jianmei Guo
Lin Tang
Kelin Li
Qingxin Ma
Shuda Luo
Ruoyu Cheng
Chaoyong Liu
author_sort Jianmei Guo
collection DOAJ
description Cancer vaccines stimulate the immune system within the body by introducing tumor antigens in various forms, such as tumor cells, tumor‐related proteins or peptides, and genes expressing tumor antigens, into the body. This activation of the immune response aims to prevent or treat tumors. Preventive cancer vaccines are primarily targeted at cancers caused by viral infections, and most cancer vaccines are currently designed as therapeutic vaccines for cancer treatment. In this review, the development of cancer vaccines, the mechanism of action, the types of antigens, and the progress of nanotechnology in therapeutic cancer vaccines are summarized. The development and application of cancer vaccines incorporating tumor‐specific antigens and nanomaterials are anticipated.
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spelling doaj.art-57b1a771621c47bdaa7d6708f17ab6952023-07-07T02:00:40ZengWiley-VCHAdvanced NanoBiomed Research2699-93072023-07-0137n/an/a10.1002/anbr.202200122Application of Nanotechnology in Therapeutic Cancer VaccinesJianmei Guo0Lin Tang1Kelin Li2Qingxin Ma3Shuda Luo4Ruoyu Cheng5Chaoyong Liu6College of Life Science and Technology Beijing University of Chemical Technology Beijing 100029 P.R. ChinaBeijing Advanced Innovation Center for Soft Matter Science and Engineering Beijing University of Chemical Technology Beijing 100029 P.R. ChinaCollege of Life Science and Technology Beijing University of Chemical Technology Beijing 100029 P.R. ChinaCollege of Life Science and Technology Beijing University of Chemical Technology Beijing 100029 P.R. ChinaCollege of Life Science and Technology Beijing University of Chemical Technology Beijing 100029 P.R. ChinaCollege of Life Science and Technology Beijing University of Chemical Technology Beijing 100029 P.R. ChinaCollege of Life Science and Technology Beijing University of Chemical Technology Beijing 100029 P.R. ChinaCancer vaccines stimulate the immune system within the body by introducing tumor antigens in various forms, such as tumor cells, tumor‐related proteins or peptides, and genes expressing tumor antigens, into the body. This activation of the immune response aims to prevent or treat tumors. Preventive cancer vaccines are primarily targeted at cancers caused by viral infections, and most cancer vaccines are currently designed as therapeutic vaccines for cancer treatment. In this review, the development of cancer vaccines, the mechanism of action, the types of antigens, and the progress of nanotechnology in therapeutic cancer vaccines are summarized. The development and application of cancer vaccines incorporating tumor‐specific antigens and nanomaterials are anticipated.https://doi.org/10.1002/anbr.202200122cancer vaccinesclinical trialsnanotechnologytherapeutictumor-specific antigens
spellingShingle Jianmei Guo
Lin Tang
Kelin Li
Qingxin Ma
Shuda Luo
Ruoyu Cheng
Chaoyong Liu
Application of Nanotechnology in Therapeutic Cancer Vaccines
Advanced NanoBiomed Research
cancer vaccines
clinical trials
nanotechnology
therapeutic
tumor-specific antigens
title Application of Nanotechnology in Therapeutic Cancer Vaccines
title_full Application of Nanotechnology in Therapeutic Cancer Vaccines
title_fullStr Application of Nanotechnology in Therapeutic Cancer Vaccines
title_full_unstemmed Application of Nanotechnology in Therapeutic Cancer Vaccines
title_short Application of Nanotechnology in Therapeutic Cancer Vaccines
title_sort application of nanotechnology in therapeutic cancer vaccines
topic cancer vaccines
clinical trials
nanotechnology
therapeutic
tumor-specific antigens
url https://doi.org/10.1002/anbr.202200122
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