Co-clustering of EphB6 and ephrinB1 in trans restrains cancer cell invasion

Co-clustering of EphB6 and ephrinB1 in trans restrains cancer cell invasion

Abstract EphB6 is an understudied ephrin receptor tyrosine pseudokinase that is downregulated in multiple types of metastatic cancers. Unlike its kinase-active counterparts which autophosphorylate and transmit signals upon intercellular interaction, little is known about how EphB6 functions in the a...

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Bibliographic Details
Main Authors: Lung-Yu Liang, Niall D. Geoghegan, Michael Mlodzianoski, Andrew Leis, Lachlan W. Whitehead, Minglyanna G. Surudoi, Samuel N. Young, Peter Janes, Doulin Shepherd, Debnath Ghosal, Kelly L. Rogers, James M. Murphy, Isabelle S. Lucet
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-06118-4

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