Depression in multiple sclerosis - review

Depression is one of the most important psychiatric comorbidities in multiple sclerosis and is associated with increased disability and poor quality of life. The diagnosis is challenging because of the overlapping symptomatology. The pathogenesis is complex and controversial, the incidence is high,...

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Bibliographic Details
Main Authors: Smaranda Maier, Rodica Balasa, Mircea Buruian, Anca Maier, Zoltan Bajko
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2015-03-01
Series:Romanian Journal of Neurology
Subjects:
Online Access:https://rjn.com.ro/articles/2015.1/RJN_2015_1_Art-04.pdf
Description
Summary:Depression is one of the most important psychiatric comorbidities in multiple sclerosis and is associated with increased disability and poor quality of life. The diagnosis is challenging because of the overlapping symptomatology. The pathogenesis is complex and controversial, the incidence is high, but is frequently under-diagnosed and under-treated. The aim of this article is to review the most important aspects of depression in multiple sclerosis as: epidemiology, pathogenesis, assessment, correlates with disability, cognition, fatigue, quality of life, suicide, the relationship with the immunomodulatory therapy, neuroimaging and treatment options.
ISSN:1843-8148
2069-6094