ANTIBODIESTOBENZO [A] PYREN, ESTRADIOL AND PROGESTERON IN WOMEN WITH EXTERNAL GENITAL ENDOMETRIOSIS
Objective – to study the social and household characteristics and specific immune responses to hormone-like xenobiotics and sex steroids in women with endometriosis. Materials and methods. A retrospective case-control study was conducted. The study included 200 women. Group I – women with a verifie...
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| Format: | Article |
| Language: | Russian |
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The Publishing House Medicine and Enlightenment
2018-12-01
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| Series: | Мать и дитя в Кузбассе |
| Subjects: | |
| Online Access: | http://mednauki.ru/index.php/MD/article/view/301 |
| _version_ | 1811319280776511488 |
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| author | Виталий Олегович Червов Наталья Владимировна Артымук Лариса Николаевна Данилова Елена Геннадьевна Поленок |
| author_facet | Виталий Олегович Червов Наталья Владимировна Артымук Лариса Николаевна Данилова Елена Геннадьевна Поленок |
| author_sort | Виталий Олегович Червов |
| collection | DOAJ |
| description | Objective – to study the social and household characteristics and specific immune responses to hormone-like xenobiotics and sex steroids in women with endometriosis.
Materials and methods. A retrospective case-control study was conducted. The study included 200 women. Group I – women with a verified diagnosis of IEG (n = 100), Group II – women with tubal genesis infertility (n = 100). Using non-competitive enzyme immunoassay, all women in the studied groups studied serum antibodies (AT) of the IgA and IgG class specific for benzo[a]pyrene (BP), estradiol (ES) and progesterone (PG). The threshold values of antibodies associated with an increased risk of endometriosis were identified.
The results. Women with endometriosis are more often subject to increased exposure to EDS, due to active and passive smoking. In patients with endometriosis, the levels of IgA and IgG antibodies to steroid hormones and benzo[a]pyrene are statistically significantly higher.
Conclusion. The effects of EDS can be considered a risk factor for endometriosis. |
| first_indexed | 2024-04-13T12:40:02Z |
| format | Article |
| id | doaj.art-57b8f465ab4341849488ad401ce5828f |
| institution | Directory Open Access Journal |
| issn | 1991-010X 2542-0968 |
| language | Russian |
| last_indexed | 2024-04-13T12:40:02Z |
| publishDate | 2018-12-01 |
| publisher | The Publishing House Medicine and Enlightenment |
| record_format | Article |
| series | Мать и дитя в Кузбассе |
| spelling | doaj.art-57b8f465ab4341849488ad401ce5828f2022-12-22T02:46:33ZrusThe Publishing House Medicine and EnlightenmentМать и дитя в Кузбассе1991-010X2542-09682018-12-011943136266ANTIBODIESTOBENZO [A] PYREN, ESTRADIOL AND PROGESTERON IN WOMEN WITH EXTERNAL GENITAL ENDOMETRIOSISВиталий Олегович Червов0Наталья Владимировна Артымук1Лариса Николаевна Данилова2Елена Геннадьевна Поленок3ФГБОУ ВО КемГМУ Минздрава России, г. КемеровоФГБОУ ВО «Кемеровский государственный медицинский университет» Минздрава РоссииГАУЗ КО ОКПЦ им. Л.А. Решетовой, г. КемеровоФГБУН ИЭЧ СО РАН ФИЦ УУХ СО РАН, г. КемеровоObjective – to study the social and household characteristics and specific immune responses to hormone-like xenobiotics and sex steroids in women with endometriosis. Materials and methods. A retrospective case-control study was conducted. The study included 200 women. Group I – women with a verified diagnosis of IEG (n = 100), Group II – women with tubal genesis infertility (n = 100). Using non-competitive enzyme immunoassay, all women in the studied groups studied serum antibodies (AT) of the IgA and IgG class specific for benzo[a]pyrene (BP), estradiol (ES) and progesterone (PG). The threshold values of antibodies associated with an increased risk of endometriosis were identified. The results. Women with endometriosis are more often subject to increased exposure to EDS, due to active and passive smoking. In patients with endometriosis, the levels of IgA and IgG antibodies to steroid hormones and benzo[a]pyrene are statistically significantly higher. Conclusion. The effects of EDS can be considered a risk factor for endometriosis.http://mednauki.ru/index.php/MD/article/view/301эндометриозксенобиотикибензо[а]пиренэстрогенпрогестеронантитела |
| spellingShingle | Виталий Олегович Червов Наталья Владимировна Артымук Лариса Николаевна Данилова Елена Геннадьевна Поленок ANTIBODIESTOBENZO [A] PYREN, ESTRADIOL AND PROGESTERON IN WOMEN WITH EXTERNAL GENITAL ENDOMETRIOSIS Мать и дитя в Кузбассе эндометриоз ксенобиотики бензо[а]пирен эстроген прогестерон антитела |
| title | ANTIBODIESTOBENZO [A] PYREN, ESTRADIOL AND PROGESTERON IN WOMEN WITH EXTERNAL GENITAL ENDOMETRIOSIS |
| title_full | ANTIBODIESTOBENZO [A] PYREN, ESTRADIOL AND PROGESTERON IN WOMEN WITH EXTERNAL GENITAL ENDOMETRIOSIS |
| title_fullStr | ANTIBODIESTOBENZO [A] PYREN, ESTRADIOL AND PROGESTERON IN WOMEN WITH EXTERNAL GENITAL ENDOMETRIOSIS |
| title_full_unstemmed | ANTIBODIESTOBENZO [A] PYREN, ESTRADIOL AND PROGESTERON IN WOMEN WITH EXTERNAL GENITAL ENDOMETRIOSIS |
| title_short | ANTIBODIESTOBENZO [A] PYREN, ESTRADIOL AND PROGESTERON IN WOMEN WITH EXTERNAL GENITAL ENDOMETRIOSIS |
| title_sort | antibodiestobenzo a pyren estradiol and progesteron in women with external genital endometriosis |
| topic | эндометриоз ксенобиотики бензо[а]пирен эстроген прогестерон антитела |
| url | http://mednauki.ru/index.php/MD/article/view/301 |
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