Clinical value of 18F-FDG PET/CT in the management of HIV-associated lymphoma

HIV is still a major public health problem. At present, HIV-associated lymphoma remains the leading cause of deaths among people living with HIV, which should be paid more attention to. 18F-fluorodeoxglucose (FDG) PET/CT has been recommended in the initial staging, restaging, response assessment and...

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Main Authors: Qi Liu, Tao Yang, Xiaoliang Chen, Yao Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1117064/full
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author Qi Liu
Tao Yang
Xiaoliang Chen
Yao Liu
author_facet Qi Liu
Tao Yang
Xiaoliang Chen
Yao Liu
author_sort Qi Liu
collection DOAJ
description HIV is still a major public health problem. At present, HIV-associated lymphoma remains the leading cause of deaths among people living with HIV, which should be paid more attention to. 18F-fluorodeoxglucose (FDG) PET/CT has been recommended in the initial staging, restaging, response assessment and prognostic prediction of lymphomas in general population. HIV-associated lymphoma is, however, a different entity from lymphoma in HIV-negative with a poorer prognosis. The ability to accurately risk-stratify HIV-infected patients with lymphoma will help guide treatment strategy and improve the prognosis. In the review, the current clinical applications of 18F-FDG PET/CT in HIV-associated lymphoma will be discussed, such as diagnosis, initial staging, response evaluation, prognostic prediction, PET-guided radiotherapy decision, and surveillance for recurrence. Moreover, future perspectives will also be presented.
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spelling doaj.art-57b9a2025ab34ee09bf19f9a9e5251e72023-01-26T13:43:35ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-01-011310.3389/fonc.2023.11170641117064Clinical value of 18F-FDG PET/CT in the management of HIV-associated lymphomaQi Liu0Tao Yang1Xiaoliang Chen2Yao Liu3Department of Nuclear Medicine, Chongqing University Cancer Hospital, Chongqing, ChinaDepartment of Hematology-Oncology, Chongqing University Cancer Hospital, Chongqing, ChinaDepartment of Nuclear Medicine, Chongqing University Cancer Hospital, Chongqing, ChinaDepartment of Hematology-Oncology, Chongqing University Cancer Hospital, Chongqing, ChinaHIV is still a major public health problem. At present, HIV-associated lymphoma remains the leading cause of deaths among people living with HIV, which should be paid more attention to. 18F-fluorodeoxglucose (FDG) PET/CT has been recommended in the initial staging, restaging, response assessment and prognostic prediction of lymphomas in general population. HIV-associated lymphoma is, however, a different entity from lymphoma in HIV-negative with a poorer prognosis. The ability to accurately risk-stratify HIV-infected patients with lymphoma will help guide treatment strategy and improve the prognosis. In the review, the current clinical applications of 18F-FDG PET/CT in HIV-associated lymphoma will be discussed, such as diagnosis, initial staging, response evaluation, prognostic prediction, PET-guided radiotherapy decision, and surveillance for recurrence. Moreover, future perspectives will also be presented.https://www.frontiersin.org/articles/10.3389/fonc.2023.1117064/fullHIVdiffuse large B-cell lymphomaBurkitt’s lymphomaHodgkin’s lymphoma18F-FDG PET
spellingShingle Qi Liu
Tao Yang
Xiaoliang Chen
Yao Liu
Clinical value of 18F-FDG PET/CT in the management of HIV-associated lymphoma
Frontiers in Oncology
HIV
diffuse large B-cell lymphoma
Burkitt’s lymphoma
Hodgkin’s lymphoma
18F-FDG PET
title Clinical value of 18F-FDG PET/CT in the management of HIV-associated lymphoma
title_full Clinical value of 18F-FDG PET/CT in the management of HIV-associated lymphoma
title_fullStr Clinical value of 18F-FDG PET/CT in the management of HIV-associated lymphoma
title_full_unstemmed Clinical value of 18F-FDG PET/CT in the management of HIV-associated lymphoma
title_short Clinical value of 18F-FDG PET/CT in the management of HIV-associated lymphoma
title_sort clinical value of 18f fdg pet ct in the management of hiv associated lymphoma
topic HIV
diffuse large B-cell lymphoma
Burkitt’s lymphoma
Hodgkin’s lymphoma
18F-FDG PET
url https://www.frontiersin.org/articles/10.3389/fonc.2023.1117064/full
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