Diagnostic Efficacy of New ECG Criteria for Left Ventricular Hypertrophy in Overweight and Obese Patients with Hypertension
Background The new electrocardiogram (ECG) criteria have higher accuracy in the diagnosis of left ventricular hypertrophy (LVH) in general population with hypertension than traditional ECG voltage criteria. However, the diagnostic efficacy of new ECG criteria for LVH in overweight and obese patients...
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| Format: | Article |
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Chinese General Practice Publishing House Co., Ltd
2022-12-01
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| Series: | Zhongguo quanke yixue |
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| Online Access: | https://www.chinagp.net/fileup/1007-9572/PDF/zx20220446.pdf |
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| author | YANG Tao, ZHANG Yongjun, ZHENG Liang, GE Xuhua |
| author_facet | YANG Tao, ZHANG Yongjun, ZHENG Liang, GE Xuhua |
| author_sort | YANG Tao, ZHANG Yongjun, ZHENG Liang, GE Xuhua |
| collection | DOAJ |
| description | Background The new electrocardiogram (ECG) criteria have higher accuracy in the diagnosis of left ventricular hypertrophy (LVH) in general population with hypertension than traditional ECG voltage criteria. However, the diagnostic efficacy of new ECG criteria for LVH in overweight and obese patients with hypertension has been rarely reported. Objective To explore the diagnostic value of new ECG indicators for LVH in overweight and obese patients with hypertension. Methods A retrospective design was used. A total of 368 overweight and obese patients with hypertension were recruited from the First Affiliated Hospital of Wannan Medical College from December 2017 to December 2020, and divided into LVH (+) group (including males with LVH>115 g/m2 and females with LVH >95 g/m2) and LVH (-) group (including males with LVH≤115 g/m2 and females with LVH≤95 g/m2) . General data were collected and compared between two groups. Intergroup comparison was also performed in terms of ultrasonic cardiography (UCG) indicators〔diastolic interventricular septal thickness (IVST) , left ventricular posterior wall thickness (LVPWT) , left ventricular mass (LVM) , left ventricular mass index (LVMI) , left ventricular ejection fraction (LVEF) 〕and ECG indicators〔QRS duration (QRSd) , corrected QT interval (QTc) , Sokolow-Lyon voltage criteria, Cornell voltage criteria, Peguero Lo-Presti voltage criteria, Cornell product〕with the accuracy of UCG indicators as the gold standard. Binary Logistic regression model was used to analyze the influencing factors of LVH in hypertension with overweight or obesity. ROC analysis was used to evaluate the diagnostic efficacy of new ECG indicators (Sokolow-Lyon voltage criteria, Cornell voltage criteria, Peguero Lo-Presti voltage criteria, Cornell product) for LVH in hypertension with overweight or obesity. Results There were statistically significant differences in sex ratio, mean age, body surface area (BSA) , SBP, DBP, β-blocker utilization rate and blood pressure control between LVH (+) and LVH (-) groups (P<0.05) . The mean values of IVST, LVPWT, LVM, LVMI, QRSd, QTc, Sokolow-Lyon voltage criteria, Cornell voltage criteria, Peguero Lo-Presti voltage criteria and Cornell product in LVH (+) group were higher than those in LVH (-) group (P<0.05) . The mean LVEF value in LVH (+) group was lower than that in LVH (-) group (P<0.05) . Age 〔OR=1.046, 95%CI (1.024, 1.069) 〕 and Sokolow-Lyon voltage criteria〔OR=1.793, 95%CI (1.305, 2.463) 〕 were influential factors for LVH risk in hypertension with overweight or obesity (P<0.05) . The AUC of Sokolow-Lyon voltage criteria, Cornell voltage criteria Peguero Lo-Presti voltage criteria and Cornell product for LVH diagnosis in hypertension with overweight or obesity was 0.674, 0.695, 0.662 and 0.722, respectively. The AUC of the combined diagnostic model with age, BSA, SBP, DBP, time of the duration of hypertension, QRSd, QTc, Sokolow-Lyon voltage criteria, Cornell voltage criteria, Peguero Lo-Presti voltage criteria, and Cornell product incorporated was 0.846. Conclusion In overweight and obese people with hypertension, the Sokolow-Lyon voltage criteria was associated with LVH. Moreover, the new ECG indicator Peguero Lo-Presti voltage criteria was less effective than Cornell product and other traditional ECG indicators in diagnosing LVH. The combined diagnostic model has proven to be with better diagnostic performance for LVH, which is recommended to be used and promoted in primary care settings with relatively unsatisfactory examination conditions. |
| first_indexed | 2024-04-24T11:53:11Z |
| format | Article |
| id | doaj.art-57bb461a0d7745979c330fa3bd33bf6e |
| institution | Directory Open Access Journal |
| issn | 1007-9572 |
| language | zho |
| last_indexed | 2024-04-24T11:53:11Z |
| publishDate | 2022-12-01 |
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| spelling | doaj.art-57bb461a0d7745979c330fa3bd33bf6e2024-04-09T06:41:42ZzhoChinese General Practice Publishing House Co., LtdZhongguo quanke yixue1007-95722022-12-0125364502450810.12114/j.issn.1007-9572.2022.0446Diagnostic Efficacy of New ECG Criteria for Left Ventricular Hypertrophy in Overweight and Obese Patients with HypertensionYANG Tao, ZHANG Yongjun, ZHENG Liang, GE Xuhua01.Department of General Practice, Yangpu Hospital, School of Medicine, Tongji University, Shanghai 200092, China;2.Department of Electrophysiology, the First Affiliated Hospital of Wannan Medical College/Yijishan Hospital, Wuhu 241001, China;3.Shanghai Heart Failure Institute, Dongfang Hospital Affiliated to Tongji University, Tongji University School of Medicine, Shanghai 200120, China;4.Shanghai Research Center for General Practice and Community Health, Shanghai 200090, ChinaBackground The new electrocardiogram (ECG) criteria have higher accuracy in the diagnosis of left ventricular hypertrophy (LVH) in general population with hypertension than traditional ECG voltage criteria. However, the diagnostic efficacy of new ECG criteria for LVH in overweight and obese patients with hypertension has been rarely reported. Objective To explore the diagnostic value of new ECG indicators for LVH in overweight and obese patients with hypertension. Methods A retrospective design was used. A total of 368 overweight and obese patients with hypertension were recruited from the First Affiliated Hospital of Wannan Medical College from December 2017 to December 2020, and divided into LVH (+) group (including males with LVH>115 g/m2 and females with LVH >95 g/m2) and LVH (-) group (including males with LVH≤115 g/m2 and females with LVH≤95 g/m2) . General data were collected and compared between two groups. Intergroup comparison was also performed in terms of ultrasonic cardiography (UCG) indicators〔diastolic interventricular septal thickness (IVST) , left ventricular posterior wall thickness (LVPWT) , left ventricular mass (LVM) , left ventricular mass index (LVMI) , left ventricular ejection fraction (LVEF) 〕and ECG indicators〔QRS duration (QRSd) , corrected QT interval (QTc) , Sokolow-Lyon voltage criteria, Cornell voltage criteria, Peguero Lo-Presti voltage criteria, Cornell product〕with the accuracy of UCG indicators as the gold standard. Binary Logistic regression model was used to analyze the influencing factors of LVH in hypertension with overweight or obesity. ROC analysis was used to evaluate the diagnostic efficacy of new ECG indicators (Sokolow-Lyon voltage criteria, Cornell voltage criteria, Peguero Lo-Presti voltage criteria, Cornell product) for LVH in hypertension with overweight or obesity. Results There were statistically significant differences in sex ratio, mean age, body surface area (BSA) , SBP, DBP, β-blocker utilization rate and blood pressure control between LVH (+) and LVH (-) groups (P<0.05) . The mean values of IVST, LVPWT, LVM, LVMI, QRSd, QTc, Sokolow-Lyon voltage criteria, Cornell voltage criteria, Peguero Lo-Presti voltage criteria and Cornell product in LVH (+) group were higher than those in LVH (-) group (P<0.05) . The mean LVEF value in LVH (+) group was lower than that in LVH (-) group (P<0.05) . Age 〔OR=1.046, 95%CI (1.024, 1.069) 〕 and Sokolow-Lyon voltage criteria〔OR=1.793, 95%CI (1.305, 2.463) 〕 were influential factors for LVH risk in hypertension with overweight or obesity (P<0.05) . The AUC of Sokolow-Lyon voltage criteria, Cornell voltage criteria Peguero Lo-Presti voltage criteria and Cornell product for LVH diagnosis in hypertension with overweight or obesity was 0.674, 0.695, 0.662 and 0.722, respectively. The AUC of the combined diagnostic model with age, BSA, SBP, DBP, time of the duration of hypertension, QRSd, QTc, Sokolow-Lyon voltage criteria, Cornell voltage criteria, Peguero Lo-Presti voltage criteria, and Cornell product incorporated was 0.846. Conclusion In overweight and obese people with hypertension, the Sokolow-Lyon voltage criteria was associated with LVH. Moreover, the new ECG indicator Peguero Lo-Presti voltage criteria was less effective than Cornell product and other traditional ECG indicators in diagnosing LVH. The combined diagnostic model has proven to be with better diagnostic performance for LVH, which is recommended to be used and promoted in primary care settings with relatively unsatisfactory examination conditions.https://www.chinagp.net/fileup/1007-9572/PDF/zx20220446.pdfoverweight|obesity|hypertension|hypertrophy, left ventricular|electrocardiography|diagnosis |
| spellingShingle | YANG Tao, ZHANG Yongjun, ZHENG Liang, GE Xuhua Diagnostic Efficacy of New ECG Criteria for Left Ventricular Hypertrophy in Overweight and Obese Patients with Hypertension Zhongguo quanke yixue overweight|obesity|hypertension|hypertrophy, left ventricular|electrocardiography|diagnosis |
| title | Diagnostic Efficacy of New ECG Criteria for Left Ventricular Hypertrophy in Overweight and Obese Patients with Hypertension |
| title_full | Diagnostic Efficacy of New ECG Criteria for Left Ventricular Hypertrophy in Overweight and Obese Patients with Hypertension |
| title_fullStr | Diagnostic Efficacy of New ECG Criteria for Left Ventricular Hypertrophy in Overweight and Obese Patients with Hypertension |
| title_full_unstemmed | Diagnostic Efficacy of New ECG Criteria for Left Ventricular Hypertrophy in Overweight and Obese Patients with Hypertension |
| title_short | Diagnostic Efficacy of New ECG Criteria for Left Ventricular Hypertrophy in Overweight and Obese Patients with Hypertension |
| title_sort | diagnostic efficacy of new ecg criteria for left ventricular hypertrophy in overweight and obese patients with hypertension |
| topic | overweight|obesity|hypertension|hypertrophy, left ventricular|electrocardiography|diagnosis |
| url | https://www.chinagp.net/fileup/1007-9572/PDF/zx20220446.pdf |
| work_keys_str_mv | AT yangtaozhangyongjunzhenglianggexuhua diagnosticefficacyofnewecgcriteriaforleftventricularhypertrophyinoverweightandobesepatientswithhypertension |