A cross-disorder PRS-pheWAS of 5 major psychiatric disorders in UK Biobank.
Psychiatric disorders are highly heritable and associated with a wide variety of social adversity and physical health problems. Using genetic liability (rather than phenotypic measures of disease) as a proxy for psychiatric disease risk can be a useful alternative for research questions that would t...
Main Authors: | Beate Leppert, Louise A C Millard, Lucy Riglin, George Davey Smith, Anita Thapar, Kate Tilling, Esther Walton, Evie Stergiakouli |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-05-01
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Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1008185 |
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