Sclerotium rolfsii lectin induces stronger inhibition of proliferation in human breast cancer cells than normal human mammary epithelial cells by induction of cell apoptosis.

Sclerotium rolfsii lectin induces stronger inhibition of proliferation in human breast cancer cells than normal human mammary epithelial cells by induction of cell apoptosis.

Sclerotium rolfsii lectin (SRL) isolated from the phytopathogenic fungus Sclerotium rolfsii has exquisite binding specificity towards O-linked, Thomsen-Freidenreich (Galβ1-3GalNAcα1-Ser/Thr, TF) associated glycans. This study investigated the influence of SRL on proliferation of human breast cancer...

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Main Authors: Mohammed Azharuddin Savanur, Sachin M Eligar, Radha Pujari, Chen Chen, Pravin Mahajan, Anita Borges, Padma Shastry, Arvind Ingle, Rajiv D Kalraiya, Bale M Swamy, Jonathan M Rhodes, Lu-Gang Yu, Shashikala R Inamdar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4217719?pdf=render

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