Perspective: Water-Filtered Infrared-A-Radiation (wIRA) – Novel Treatment Options for Chlamydial Infections?
Water-filtered infrared-A-radiation (wIRA) is a promising therapeutic method, which is particularly used as supportive treatment for wound closure, and wound infection treatment and prevention. High penetration properties of the heat field and beneficial effects on wound healing processes predispose...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2019-05-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fmicb.2019.01053/full |
| _version_ | 1828378449093328896 |
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| author | Jasmin Kuratli Nicole Borel |
| author_facet | Jasmin Kuratli Nicole Borel |
| author_sort | Jasmin Kuratli |
| collection | DOAJ |
| description | Water-filtered infrared-A-radiation (wIRA) is a promising therapeutic method, which is particularly used as supportive treatment for wound closure, and wound infection treatment and prevention. High penetration properties of the heat field and beneficial effects on wound healing processes predispose wIRA irradiation to be a non-invasive treatment method for bacterial infections in superficial tissues. Since Chlamydia trachomatis still represents the leading cause of infectious blindness in third world countries (WHO http://www.who.int/topics/trachoma/en/) and wIRA displays beneficial effects on chlamydial infections in vitro without inducing cellular damage in ex vivo eye models and also shows beneficial effects on wound healing, this irradiation technique might represent a promising future treatment for trachoma patients. To this end, further studies investigating shorter irradiation times or irradiation of Chlamydia in chronic infections [the chlamydial stress response (Bavoil, 2014)] as well as safety studies in animal models should clearly be performed. |
| first_indexed | 2024-04-14T08:27:04Z |
| format | Article |
| id | doaj.art-57bfb617a24748dfa394b3716c6fa2b9 |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-04-14T08:27:04Z |
| publishDate | 2019-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-57bfb617a24748dfa394b3716c6fa2b92022-12-22T02:04:02ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2019-05-011010.3389/fmicb.2019.01053453337Perspective: Water-Filtered Infrared-A-Radiation (wIRA) – Novel Treatment Options for Chlamydial Infections?Jasmin KuratliNicole BorelWater-filtered infrared-A-radiation (wIRA) is a promising therapeutic method, which is particularly used as supportive treatment for wound closure, and wound infection treatment and prevention. High penetration properties of the heat field and beneficial effects on wound healing processes predispose wIRA irradiation to be a non-invasive treatment method for bacterial infections in superficial tissues. Since Chlamydia trachomatis still represents the leading cause of infectious blindness in third world countries (WHO http://www.who.int/topics/trachoma/en/) and wIRA displays beneficial effects on chlamydial infections in vitro without inducing cellular damage in ex vivo eye models and also shows beneficial effects on wound healing, this irradiation technique might represent a promising future treatment for trachoma patients. To this end, further studies investigating shorter irradiation times or irradiation of Chlamydia in chronic infections [the chlamydial stress response (Bavoil, 2014)] as well as safety studies in animal models should clearly be performed.https://www.frontiersin.org/article/10.3389/fmicb.2019.01053/fullChlamydia trachomatiswIRA irradiationwIRA/VISwound healingwound infectionalternative treatment strategies |
| spellingShingle | Jasmin Kuratli Nicole Borel Perspective: Water-Filtered Infrared-A-Radiation (wIRA) – Novel Treatment Options for Chlamydial Infections? Frontiers in Microbiology Chlamydia trachomatis wIRA irradiation wIRA/VIS wound healing wound infection alternative treatment strategies |
| title | Perspective: Water-Filtered Infrared-A-Radiation (wIRA) – Novel Treatment Options for Chlamydial Infections? |
| title_full | Perspective: Water-Filtered Infrared-A-Radiation (wIRA) – Novel Treatment Options for Chlamydial Infections? |
| title_fullStr | Perspective: Water-Filtered Infrared-A-Radiation (wIRA) – Novel Treatment Options for Chlamydial Infections? |
| title_full_unstemmed | Perspective: Water-Filtered Infrared-A-Radiation (wIRA) – Novel Treatment Options for Chlamydial Infections? |
| title_short | Perspective: Water-Filtered Infrared-A-Radiation (wIRA) – Novel Treatment Options for Chlamydial Infections? |
| title_sort | perspective water filtered infrared a radiation wira novel treatment options for chlamydial infections |
| topic | Chlamydia trachomatis wIRA irradiation wIRA/VIS wound healing wound infection alternative treatment strategies |
| url | https://www.frontiersin.org/article/10.3389/fmicb.2019.01053/full |
| work_keys_str_mv | AT jasminkuratli perspectivewaterfilteredinfraredaradiationwiranoveltreatmentoptionsforchlamydialinfections AT nicoleborel perspectivewaterfilteredinfraredaradiationwiranoveltreatmentoptionsforchlamydialinfections |