Constitutive activation of Gli2 impairs bone formation in postnatal growing mice.

Indian hedgehog (Ihh) signaling is indispensable for osteoblast differentiation during endochondral bone development in the mouse embryo. We have previously shown that the Gli2 transcription activator critically mediates Ihh function in osteoblastogenesis. To explore the possibility that activation...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Kyu Sang Joeng, Fanxin Long
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: Public Library of Science (PLoS) 2013-01-01
Sarja:PLoS ONE
Linkit:http://europepmc.org/articles/PMC3559391?pdf=render