Molecular epidemiology of dengue viruses in Brazil
Dengue viruses (DEN) are found as four antigenically distinct serotypes designated DEN-1, 2, 3, and 4. Laboratory evidence that strain-intratypical variation occurs among DEN viruses has been demonstrated since the 1970s, although only with the advances in molecular technologies has it been possible...
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Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz
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Series: | Cadernos de Saúde Pública |
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author | Rita Maria Ribeiro Nogueira Marize Pereira Miagostovich Hermann Gonçalves Schatzmayr |
author_facet | Rita Maria Ribeiro Nogueira Marize Pereira Miagostovich Hermann Gonçalves Schatzmayr |
author_sort | Rita Maria Ribeiro Nogueira |
collection | DOAJ |
description | Dengue viruses (DEN) are found as four antigenically distinct serotypes designated DEN-1, 2, 3, and 4. Laboratory evidence that strain-intratypical variation occurs among DEN viruses has been demonstrated since the 1970s, although only with the advances in molecular technologies has it been possible to determine the genetic variability of each serotype. Genotypical identification has proven to be a useful tool for determining the origin and spread of epidemics and to correlate virulence of strains. In this report we present the results of molecular epidemiological studies with the DEN-1 and DEN-2 viruses that caused dengue epidemics in Brazil during the last decade. |
first_indexed | 2024-04-13T22:26:43Z |
format | Article |
id | doaj.art-57c32a5f682b429391a0ada0e8c79332 |
institution | Directory Open Access Journal |
issn | 1678-4464 |
language | English |
last_indexed | 2024-04-13T22:26:43Z |
publisher | Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz |
record_format | Article |
series | Cadernos de Saúde Pública |
spelling | doaj.art-57c32a5f682b429391a0ada0e8c793322022-12-22T02:27:02ZengEscola Nacional de Saúde Pública, Fundação Oswaldo CruzCadernos de Saúde Pública1678-4464161205211S0102-311X2000000100021Molecular epidemiology of dengue viruses in BrazilRita Maria Ribeiro Nogueira0Marize Pereira Miagostovich1Hermann Gonçalves Schatzmayr2Fundação Oswaldo CruzFundação Oswaldo CruzFundação Oswaldo CruzDengue viruses (DEN) are found as four antigenically distinct serotypes designated DEN-1, 2, 3, and 4. Laboratory evidence that strain-intratypical variation occurs among DEN viruses has been demonstrated since the 1970s, although only with the advances in molecular technologies has it been possible to determine the genetic variability of each serotype. Genotypical identification has proven to be a useful tool for determining the origin and spread of epidemics and to correlate virulence of strains. In this report we present the results of molecular epidemiological studies with the DEN-1 and DEN-2 viruses that caused dengue epidemics in Brazil during the last decade.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2000000100021&lng=en&tlng=enVírus DengueDengueEpidemiologia Molecular |
spellingShingle | Rita Maria Ribeiro Nogueira Marize Pereira Miagostovich Hermann Gonçalves Schatzmayr Molecular epidemiology of dengue viruses in Brazil Cadernos de Saúde Pública Vírus Dengue Dengue Epidemiologia Molecular |
title | Molecular epidemiology of dengue viruses in Brazil |
title_full | Molecular epidemiology of dengue viruses in Brazil |
title_fullStr | Molecular epidemiology of dengue viruses in Brazil |
title_full_unstemmed | Molecular epidemiology of dengue viruses in Brazil |
title_short | Molecular epidemiology of dengue viruses in Brazil |
title_sort | molecular epidemiology of dengue viruses in brazil |
topic | Vírus Dengue Dengue Epidemiologia Molecular |
url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2000000100021&lng=en&tlng=en |
work_keys_str_mv | AT ritamariaribeironogueira molecularepidemiologyofdenguevirusesinbrazil AT marizepereiramiagostovich molecularepidemiologyofdenguevirusesinbrazil AT hermanngoncalvesschatzmayr molecularepidemiologyofdenguevirusesinbrazil |