Molecular epidemiology of dengue viruses in Brazil

Dengue viruses (DEN) are found as four antigenically distinct serotypes designated DEN-1, 2, 3, and 4. Laboratory evidence that strain-intratypical variation occurs among DEN viruses has been demonstrated since the 1970s, although only with the advances in molecular technologies has it been possible...

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Main Authors: Rita Maria Ribeiro Nogueira, Marize Pereira Miagostovich, Hermann Gonçalves Schatzmayr
Format: Article
Language:English
Published: Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz
Series:Cadernos de Saúde Pública
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2000000100021&lng=en&tlng=en
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author Rita Maria Ribeiro Nogueira
Marize Pereira Miagostovich
Hermann Gonçalves Schatzmayr
author_facet Rita Maria Ribeiro Nogueira
Marize Pereira Miagostovich
Hermann Gonçalves Schatzmayr
author_sort Rita Maria Ribeiro Nogueira
collection DOAJ
description Dengue viruses (DEN) are found as four antigenically distinct serotypes designated DEN-1, 2, 3, and 4. Laboratory evidence that strain-intratypical variation occurs among DEN viruses has been demonstrated since the 1970s, although only with the advances in molecular technologies has it been possible to determine the genetic variability of each serotype. Genotypical identification has proven to be a useful tool for determining the origin and spread of epidemics and to correlate virulence of strains. In this report we present the results of molecular epidemiological studies with the DEN-1 and DEN-2 viruses that caused dengue epidemics in Brazil during the last decade.
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spelling doaj.art-57c32a5f682b429391a0ada0e8c793322022-12-22T02:27:02ZengEscola Nacional de Saúde Pública, Fundação Oswaldo CruzCadernos de Saúde Pública1678-4464161205211S0102-311X2000000100021Molecular epidemiology of dengue viruses in BrazilRita Maria Ribeiro Nogueira0Marize Pereira Miagostovich1Hermann Gonçalves Schatzmayr2Fundação Oswaldo CruzFundação Oswaldo CruzFundação Oswaldo CruzDengue viruses (DEN) are found as four antigenically distinct serotypes designated DEN-1, 2, 3, and 4. Laboratory evidence that strain-intratypical variation occurs among DEN viruses has been demonstrated since the 1970s, although only with the advances in molecular technologies has it been possible to determine the genetic variability of each serotype. Genotypical identification has proven to be a useful tool for determining the origin and spread of epidemics and to correlate virulence of strains. In this report we present the results of molecular epidemiological studies with the DEN-1 and DEN-2 viruses that caused dengue epidemics in Brazil during the last decade.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2000000100021&lng=en&tlng=enVírus DengueDengueEpidemiologia Molecular
spellingShingle Rita Maria Ribeiro Nogueira
Marize Pereira Miagostovich
Hermann Gonçalves Schatzmayr
Molecular epidemiology of dengue viruses in Brazil
Cadernos de Saúde Pública
Vírus Dengue
Dengue
Epidemiologia Molecular
title Molecular epidemiology of dengue viruses in Brazil
title_full Molecular epidemiology of dengue viruses in Brazil
title_fullStr Molecular epidemiology of dengue viruses in Brazil
title_full_unstemmed Molecular epidemiology of dengue viruses in Brazil
title_short Molecular epidemiology of dengue viruses in Brazil
title_sort molecular epidemiology of dengue viruses in brazil
topic Vírus Dengue
Dengue
Epidemiologia Molecular
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2000000100021&lng=en&tlng=en
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AT hermanngoncalvesschatzmayr molecularepidemiologyofdenguevirusesinbrazil