Magnitude of early postoperative hypoxemia and its associated factors among adult patients who undergo emergency surgery under general anesthesia at Jimma Medical Center, Jimma, Southwest Ethiopia, 2021: a prospective observational study
Abstract Purpose Emergency surgical procedures involve considerable risks. Among these, early postoperative hypoxemia (EPH) is a frequent anesthetic complication in the post-anesthetic care unit (PACU). There is a great concern for EPH among health professionals, specifically, those providing emerge...
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-01-01
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| Series: | Perioperative Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13741-022-00288-7 |
| _version_ | 1797958552320475136 |
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| author | Mitiku Berhanu Negashu Dadi Berhanu Mengistu Zemenu Muluken Ashenafi Tolesa Tajera Tageza Megersa Kalbesa Gezahegn Tesfaye Belay Zawdie |
| author_facet | Mitiku Berhanu Negashu Dadi Berhanu Mengistu Zemenu Muluken Ashenafi Tolesa Tajera Tageza Megersa Kalbesa Gezahegn Tesfaye Belay Zawdie |
| author_sort | Mitiku Berhanu |
| collection | DOAJ |
| description | Abstract Purpose Emergency surgical procedures involve considerable risks. Among these, early postoperative hypoxemia (EPH) is a frequent anesthetic complication in the post-anesthetic care unit (PACU). There is a great concern for EPH among health professionals, specifically, those providing emergency surgery during the nighttime. This raised anesthesia-ended time-related risk of EPH question. Thus, this study aimed to determine the magnitude of EPH and its associated factors among adult patients who undergo emergency surgery under general anesthesia. Methods A prospective observational study through a consecutive sampling technique was conducted. Binary logistic regression analysis was used to identify associated risk factors. All variables that were found statistically significant on bivariable analysis were entered into a multivariable logistic regression analysis. Result Of 352 patients who had undergone emergency surgery, 149 (42.3%) patients developed EPH. Factors significantly associated with EPH were anesthesia ended during nighttime (AOR = 1.76, 95%CI [1.01, 3.05], p = 0.045), ASA III (AOR = 12.35, 95%CI: [4.5, 34.02], p ≤ 0.001), age greater than 55 (AOR = 3.2, 95%CI: [1.7, 5.91], p ≤ 0.001), surgery duration greater than 2 h (AOR = 2.012, 95%CI: [1.2, 3.51], p = 0.014), hypotension (AOR = 10.3, 95%CI: [2.4, 44.16], p = 0.002), muscular strength score zero (AOR = 2.944, 95%CI: [1.8, 4.82], p ≤ 0.001), and preoperative oxygen saturation less than 95% (AOR = 2.371, 95%CI: [1.35,4.16], p = 0.003). Conclusion The magnitude of EPH among patients who have undergone emergency surgery was high and thus recommended that oxygen should be provided timely to decrease it. Identified risk factors were night-time ended anesthesia, ASA III, age greater than 55, surgery duration greater than 2 h, hypotension, muscular strength score zero, and preoperative oxygen saturation less than 95%. This study found anesthesia ended during early morning favors early morning early postoperative hypoxemia (EMEPH). To avert EMEPH, the anesthetist should avoid factors that favor the circadian rhythm of the lung-based early morning anesthesia augmented EPH. |
| first_indexed | 2024-04-11T00:20:40Z |
| format | Article |
| id | doaj.art-57c68fbafa7a4708b111ffe8e9846ef6 |
| institution | Directory Open Access Journal |
| issn | 2047-0525 |
| language | English |
| last_indexed | 2024-04-11T00:20:40Z |
| publishDate | 2023-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Perioperative Medicine |
| spelling | doaj.art-57c68fbafa7a4708b111ffe8e9846ef62023-01-08T12:17:05ZengBMCPerioperative Medicine2047-05252023-01-0112111010.1186/s13741-022-00288-7Magnitude of early postoperative hypoxemia and its associated factors among adult patients who undergo emergency surgery under general anesthesia at Jimma Medical Center, Jimma, Southwest Ethiopia, 2021: a prospective observational studyMitiku Berhanu0Negashu Dadi1Berhanu Mengistu2Zemenu Muluken3Ashenafi Tolesa4Tajera Tageza5Megersa Kalbesa6Gezahegn Tesfaye7Belay Zawdie8Department of Anesthesia, Institute of Health Science, Jimma UniversityDepartment of Anesthesia, Institute of Health Science, Jimma UniversityDepartment of Anesthesia, Institute of Health Science, Jimma UniversityDepartment of Anesthesia, Institute of Health Science, Jimma UniversityDepartment of Anesthesia, Institute of Health Science, Jimma UniversityDepartment of Anesthesia, College of Health Science, Hawassa UniversityDepartment of Anesthesia, Institute of Health Science, Jimma UniversityDepartment of Anesthesia, Institute of Health Science, Jimma UniversityDepartment of Biomedical Science, Institute of Health Science, Jimma UniversityAbstract Purpose Emergency surgical procedures involve considerable risks. Among these, early postoperative hypoxemia (EPH) is a frequent anesthetic complication in the post-anesthetic care unit (PACU). There is a great concern for EPH among health professionals, specifically, those providing emergency surgery during the nighttime. This raised anesthesia-ended time-related risk of EPH question. Thus, this study aimed to determine the magnitude of EPH and its associated factors among adult patients who undergo emergency surgery under general anesthesia. Methods A prospective observational study through a consecutive sampling technique was conducted. Binary logistic regression analysis was used to identify associated risk factors. All variables that were found statistically significant on bivariable analysis were entered into a multivariable logistic regression analysis. Result Of 352 patients who had undergone emergency surgery, 149 (42.3%) patients developed EPH. Factors significantly associated with EPH were anesthesia ended during nighttime (AOR = 1.76, 95%CI [1.01, 3.05], p = 0.045), ASA III (AOR = 12.35, 95%CI: [4.5, 34.02], p ≤ 0.001), age greater than 55 (AOR = 3.2, 95%CI: [1.7, 5.91], p ≤ 0.001), surgery duration greater than 2 h (AOR = 2.012, 95%CI: [1.2, 3.51], p = 0.014), hypotension (AOR = 10.3, 95%CI: [2.4, 44.16], p = 0.002), muscular strength score zero (AOR = 2.944, 95%CI: [1.8, 4.82], p ≤ 0.001), and preoperative oxygen saturation less than 95% (AOR = 2.371, 95%CI: [1.35,4.16], p = 0.003). Conclusion The magnitude of EPH among patients who have undergone emergency surgery was high and thus recommended that oxygen should be provided timely to decrease it. Identified risk factors were night-time ended anesthesia, ASA III, age greater than 55, surgery duration greater than 2 h, hypotension, muscular strength score zero, and preoperative oxygen saturation less than 95%. This study found anesthesia ended during early morning favors early morning early postoperative hypoxemia (EMEPH). To avert EMEPH, the anesthetist should avoid factors that favor the circadian rhythm of the lung-based early morning anesthesia augmented EPH.https://doi.org/10.1186/s13741-022-00288-7EPHPostoperative recovery periodCircadian rhythm of lungJimma Medical Center |
| spellingShingle | Mitiku Berhanu Negashu Dadi Berhanu Mengistu Zemenu Muluken Ashenafi Tolesa Tajera Tageza Megersa Kalbesa Gezahegn Tesfaye Belay Zawdie Magnitude of early postoperative hypoxemia and its associated factors among adult patients who undergo emergency surgery under general anesthesia at Jimma Medical Center, Jimma, Southwest Ethiopia, 2021: a prospective observational study Perioperative Medicine EPH Postoperative recovery period Circadian rhythm of lung Jimma Medical Center |
| title | Magnitude of early postoperative hypoxemia and its associated factors among adult patients who undergo emergency surgery under general anesthesia at Jimma Medical Center, Jimma, Southwest Ethiopia, 2021: a prospective observational study |
| title_full | Magnitude of early postoperative hypoxemia and its associated factors among adult patients who undergo emergency surgery under general anesthesia at Jimma Medical Center, Jimma, Southwest Ethiopia, 2021: a prospective observational study |
| title_fullStr | Magnitude of early postoperative hypoxemia and its associated factors among adult patients who undergo emergency surgery under general anesthesia at Jimma Medical Center, Jimma, Southwest Ethiopia, 2021: a prospective observational study |
| title_full_unstemmed | Magnitude of early postoperative hypoxemia and its associated factors among adult patients who undergo emergency surgery under general anesthesia at Jimma Medical Center, Jimma, Southwest Ethiopia, 2021: a prospective observational study |
| title_short | Magnitude of early postoperative hypoxemia and its associated factors among adult patients who undergo emergency surgery under general anesthesia at Jimma Medical Center, Jimma, Southwest Ethiopia, 2021: a prospective observational study |
| title_sort | magnitude of early postoperative hypoxemia and its associated factors among adult patients who undergo emergency surgery under general anesthesia at jimma medical center jimma southwest ethiopia 2021 a prospective observational study |
| topic | EPH Postoperative recovery period Circadian rhythm of lung Jimma Medical Center |
| url | https://doi.org/10.1186/s13741-022-00288-7 |
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