Efficacy of acupuncture for whiplash injury: a systematic review and meta-analysis
Objectives This study aimed to establish clinical evidence for acupuncture by analysing data from trials that demonstrated the efficacy of acupuncture for whiplash-associated disorder (WAD) with the following research question: Is acupuncture treatment effective for symptom alleviation in patients w...
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BMJ Publishing Group
2024-01-01
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Series: | BMJ Open |
Online Access: | https://bmjopen.bmj.com/content/14/1/e077700.full |
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author | In Heo Man-Suk Hwang Eui-Hyoung Hwang Byung-Cheul Shin Sun-Young Park Sang-Hyun Lee |
author_facet | In Heo Man-Suk Hwang Eui-Hyoung Hwang Byung-Cheul Shin Sun-Young Park Sang-Hyun Lee |
author_sort | In Heo |
collection | DOAJ |
description | Objectives This study aimed to establish clinical evidence for acupuncture by analysing data from trials that demonstrated the efficacy of acupuncture for whiplash-associated disorder (WAD) with the following research question: Is acupuncture treatment effective for symptom alleviation in patients with WAD compared with other usual care?Design A systematic review and meta-analysis.Data sources PubMed, Ovid Medline, Embase, The Cochrane Library, China National Knowledge Infrastructure, ScienceOn, KMBASE, Korean Studies Information Service System, Korea Med, Oriental Medicine Advanced Searching Integrated System and Research Information Sharing Service were searched from their inception to 1 October 2023.Eligibility criteria We included randomised controlled trials (RCTs) using acupuncture on patients with WAD. The outcomes were the pain visual analogue scale (VAS) score or numerical rating scale score for neck pain, the range of motion (ROM) of the neck, the Neck Disability Index and safety.Data extraction and synthesis Two independent researchers analysed and extracted data from the selected literatures. The risk of bias and the quality of evidence were assessed according to the Cochrane Handbook for Systematic Reviews of Interventions and the Grading of Recommendations Assessment, Development, and Evaluation method, respectively.Results A total of 525 patients with WAD from eight RCTs were included in this study. The meta-analysis revealed that the outcomes showed significant differences in the pain VAS score (standard mean difference (SMD): −0.57 (–0.86 to –0.28), p<0.001) and ROM-extension (SMD: 0.47 (0.05 to 0.89), p=0.03). The risk of bias assessment revealed that four studies published after 2012 (50%, 4 out of 8 studies) showed low bias in most domains. The pain VAS score was graded as having moderate certainty.Conclusion Acupuncture may have clinical value in pain reduction and increasing the ROM for patients with WAD. High-quality RCTs must be conducted to confirm the efficacy of acupuncture in patients with WAD.Trial registration number PROSPERO CRD42021261595. |
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issn | 2044-6055 |
language | English |
last_indexed | 2024-03-07T21:54:14Z |
publishDate | 2024-01-01 |
publisher | BMJ Publishing Group |
record_format | Article |
series | BMJ Open |
spelling | doaj.art-57c89dd4979c49d5a5d277a375f514062024-02-24T21:40:08ZengBMJ Publishing GroupBMJ Open2044-60552024-01-0114110.1136/bmjopen-2023-077700Efficacy of acupuncture for whiplash injury: a systematic review and meta-analysisIn Heo0Man-Suk Hwang1Eui-Hyoung Hwang2Byung-Cheul Shin3Sun-Young Park4Sang-Hyun Lee53rd Division of Clinical Medicine, Pusan National University School of Korean Medicine, Yangsan, Gyeongsangnam-do, Korea (the Republic of)3rd Division of Clinical Medicine, Pusan National University School of Korean Medicine, Yangsan, Gyeongsangnam-do, Korea (the Republic of)3rd Division of Clinical Medicine, Pusan National University School of Korean Medicine, Yangsan, Gyeongsangnam-do, Korea (the Republic of)3rd Division of Clinical Medicine, Pusan National University School of Korean Medicine, Yangsan, Gyeongsangnam-do, Korea (the Republic of)3rd Division of Clinical Medicine, Pusan National University School of Korean Medicine, Yangsan, Gyeongsangnam-do, Korea (the Republic of)Department of Korean Medicine, Pusan National University Graduate School, Yangsan, Gyeongnam, Korea (the Republic of)Objectives This study aimed to establish clinical evidence for acupuncture by analysing data from trials that demonstrated the efficacy of acupuncture for whiplash-associated disorder (WAD) with the following research question: Is acupuncture treatment effective for symptom alleviation in patients with WAD compared with other usual care?Design A systematic review and meta-analysis.Data sources PubMed, Ovid Medline, Embase, The Cochrane Library, China National Knowledge Infrastructure, ScienceOn, KMBASE, Korean Studies Information Service System, Korea Med, Oriental Medicine Advanced Searching Integrated System and Research Information Sharing Service were searched from their inception to 1 October 2023.Eligibility criteria We included randomised controlled trials (RCTs) using acupuncture on patients with WAD. The outcomes were the pain visual analogue scale (VAS) score or numerical rating scale score for neck pain, the range of motion (ROM) of the neck, the Neck Disability Index and safety.Data extraction and synthesis Two independent researchers analysed and extracted data from the selected literatures. The risk of bias and the quality of evidence were assessed according to the Cochrane Handbook for Systematic Reviews of Interventions and the Grading of Recommendations Assessment, Development, and Evaluation method, respectively.Results A total of 525 patients with WAD from eight RCTs were included in this study. The meta-analysis revealed that the outcomes showed significant differences in the pain VAS score (standard mean difference (SMD): −0.57 (–0.86 to –0.28), p<0.001) and ROM-extension (SMD: 0.47 (0.05 to 0.89), p=0.03). The risk of bias assessment revealed that four studies published after 2012 (50%, 4 out of 8 studies) showed low bias in most domains. The pain VAS score was graded as having moderate certainty.Conclusion Acupuncture may have clinical value in pain reduction and increasing the ROM for patients with WAD. High-quality RCTs must be conducted to confirm the efficacy of acupuncture in patients with WAD.Trial registration number PROSPERO CRD42021261595.https://bmjopen.bmj.com/content/14/1/e077700.full |
spellingShingle | In Heo Man-Suk Hwang Eui-Hyoung Hwang Byung-Cheul Shin Sun-Young Park Sang-Hyun Lee Efficacy of acupuncture for whiplash injury: a systematic review and meta-analysis BMJ Open |
title | Efficacy of acupuncture for whiplash injury: a systematic review and meta-analysis |
title_full | Efficacy of acupuncture for whiplash injury: a systematic review and meta-analysis |
title_fullStr | Efficacy of acupuncture for whiplash injury: a systematic review and meta-analysis |
title_full_unstemmed | Efficacy of acupuncture for whiplash injury: a systematic review and meta-analysis |
title_short | Efficacy of acupuncture for whiplash injury: a systematic review and meta-analysis |
title_sort | efficacy of acupuncture for whiplash injury a systematic review and meta analysis |
url | https://bmjopen.bmj.com/content/14/1/e077700.full |
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