Current state of stem cell research in non-human primates: an overview
The remarkable similarity between non-human primates (NHPs) and humans establishes them as essential models for understanding human biology and diseases, as well as for developing novel therapeutic strategies, thereby providing more comprehensive reference data for clinical treatment. Pluripotent st...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
De Gruyter
2023-08-01
|
Series: | Medical Review |
Subjects: | |
Online Access: | https://doi.org/10.1515/mr-2023-0035 |
_version_ | 1827160600984158208 |
---|---|
author | Wu Junmo Shi Yuxi Yang Shanshan Tang Zengli Li Zifan Li Zhuoyao Zuo Jiawei Ji Weizhi Niu Yuyu |
author_facet | Wu Junmo Shi Yuxi Yang Shanshan Tang Zengli Li Zifan Li Zhuoyao Zuo Jiawei Ji Weizhi Niu Yuyu |
author_sort | Wu Junmo |
collection | DOAJ |
description | The remarkable similarity between non-human primates (NHPs) and humans establishes them as essential models for understanding human biology and diseases, as well as for developing novel therapeutic strategies, thereby providing more comprehensive reference data for clinical treatment. Pluripotent stem cells such as embryonic stem cells and induced pluripotent stem cells provide unprecedented opportunities for cell therapies against intractable diseases and injuries. As continue to harness the potential of these biotechnological therapies, NHPs are increasingly being employed in preclinical trials, serving as a pivotal tool to evaluate the safety and efficacy of these interventions. Here, we review the recent advancements in the fundamental research of stem cells and the progress made in studies involving NHPs. |
first_indexed | 2024-03-09T10:51:21Z |
format | Article |
id | doaj.art-57cb2ecdec1c42eeb737dc1a9bde9586 |
institution | Directory Open Access Journal |
issn | 2749-9642 |
language | English |
last_indexed | 2025-03-21T00:15:37Z |
publishDate | 2023-08-01 |
publisher | De Gruyter |
record_format | Article |
series | Medical Review |
spelling | doaj.art-57cb2ecdec1c42eeb737dc1a9bde95862024-08-03T09:20:42ZengDe GruyterMedical Review2749-96422023-08-013427730410.1515/mr-2023-0035Current state of stem cell research in non-human primates: an overviewWu Junmo0Shi Yuxi1Yang Shanshan2Tang Zengli3Li Zifan4Li Zhuoyao5Zuo Jiawei6Ji Weizhi7Niu Yuyu8Kunming University of Science and Technology, Kunming, Yunnan Province, ChinaKunming University of Science and Technology, Kunming, Yunnan Province, ChinaKunming University of Science and Technology, Kunming, Yunnan Province, ChinaKunming University of Science and Technology, Kunming, Yunnan Province, ChinaKunming University of Science and Technology, Kunming, Yunnan Province, ChinaKunming University of Science and Technology, Kunming, Yunnan Province, ChinaKunming University of Science and Technology, Kunming, Yunnan Province, ChinaKunming University of Science and Technology, Kunming, Yunnan Province, ChinaKunming University of Science and Technology, Kunming, Yunnan Province, ChinaThe remarkable similarity between non-human primates (NHPs) and humans establishes them as essential models for understanding human biology and diseases, as well as for developing novel therapeutic strategies, thereby providing more comprehensive reference data for clinical treatment. Pluripotent stem cells such as embryonic stem cells and induced pluripotent stem cells provide unprecedented opportunities for cell therapies against intractable diseases and injuries. As continue to harness the potential of these biotechnological therapies, NHPs are increasingly being employed in preclinical trials, serving as a pivotal tool to evaluate the safety and efficacy of these interventions. Here, we review the recent advancements in the fundamental research of stem cells and the progress made in studies involving NHPs.https://doi.org/10.1515/mr-2023-0035non-human primatescell therapystem cell |
spellingShingle | Wu Junmo Shi Yuxi Yang Shanshan Tang Zengli Li Zifan Li Zhuoyao Zuo Jiawei Ji Weizhi Niu Yuyu Current state of stem cell research in non-human primates: an overview Medical Review non-human primates cell therapy stem cell |
title | Current state of stem cell research in non-human primates: an overview |
title_full | Current state of stem cell research in non-human primates: an overview |
title_fullStr | Current state of stem cell research in non-human primates: an overview |
title_full_unstemmed | Current state of stem cell research in non-human primates: an overview |
title_short | Current state of stem cell research in non-human primates: an overview |
title_sort | current state of stem cell research in non human primates an overview |
topic | non-human primates cell therapy stem cell |
url | https://doi.org/10.1515/mr-2023-0035 |
work_keys_str_mv | AT wujunmo currentstateofstemcellresearchinnonhumanprimatesanoverview AT shiyuxi currentstateofstemcellresearchinnonhumanprimatesanoverview AT yangshanshan currentstateofstemcellresearchinnonhumanprimatesanoverview AT tangzengli currentstateofstemcellresearchinnonhumanprimatesanoverview AT lizifan currentstateofstemcellresearchinnonhumanprimatesanoverview AT lizhuoyao currentstateofstemcellresearchinnonhumanprimatesanoverview AT zuojiawei currentstateofstemcellresearchinnonhumanprimatesanoverview AT jiweizhi currentstateofstemcellresearchinnonhumanprimatesanoverview AT niuyuyu currentstateofstemcellresearchinnonhumanprimatesanoverview |