Tyrosine kinase receptor inhibitor as a molecularly targeted therapy for solid tumors
Advances in solid tumor treatment have been enormous in the past decade, especially molecularly targeted therapy, for which aberrant molecules or biological pathways relating to tumor growth and development have been targeted specifically. Molecularly targeted therapy agents show activity against sp...
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| Format: | Article |
| Language: | English |
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Prince of Songkla University
2006-01-01
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| Series: | Journal of Health Science and Medical Research (JHSMR) |
| Subjects: | |
| Online Access: | https://www.jhsmr.org/index.php/jhsmr/article/view/557 |
| _version_ | 1811268228298571776 |
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| author | P Sunpaweravong |
| author_facet | P Sunpaweravong |
| author_sort | P Sunpaweravong |
| collection | DOAJ |
| description | Advances in solid tumor treatment have been enormous in the past decade, especially molecularly targeted therapy, for which aberrant molecules or biological pathways relating to tumor growth and development have been targeted specifically. Molecularly targeted therapy agents show activity against specific tumor cells with little effect on normal vital organs or tissues, making them a more tolerable therapeutic approach for patients than chemotherapeutic agents. Tyrosine kinase receptor inhibitors are molecularly targeted therapeutic agents that inhibit signal transduction pathways. To date, a number of agents in this category have been approved for solid cancer treatment such as in lung, breast, and colon cancers. This review highlights the role of the approved tyrosine kinase receptor inhibitors for solid tumor therapy. |
| first_indexed | 2024-04-12T21:18:03Z |
| format | Article |
| id | doaj.art-57cb30d2b2234db9b92ce60bfae4639b |
| institution | Directory Open Access Journal |
| issn | 2586-9981 2630-0559 |
| language | English |
| last_indexed | 2024-04-12T21:18:03Z |
| publishDate | 2006-01-01 |
| publisher | Prince of Songkla University |
| record_format | Article |
| series | Journal of Health Science and Medical Research (JHSMR) |
| spelling | doaj.art-57cb30d2b2234db9b92ce60bfae4639b2022-12-22T03:16:23ZengPrince of Songkla UniversityJournal of Health Science and Medical Research (JHSMR)2586-99812630-05592006-01-012414352571Tyrosine kinase receptor inhibitor as a molecularly targeted therapy for solid tumorsP Sunpaweravong0Unit of Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110,Advances in solid tumor treatment have been enormous in the past decade, especially molecularly targeted therapy, for which aberrant molecules or biological pathways relating to tumor growth and development have been targeted specifically. Molecularly targeted therapy agents show activity against specific tumor cells with little effect on normal vital organs or tissues, making them a more tolerable therapeutic approach for patients than chemotherapeutic agents. Tyrosine kinase receptor inhibitors are molecularly targeted therapeutic agents that inhibit signal transduction pathways. To date, a number of agents in this category have been approved for solid cancer treatment such as in lung, breast, and colon cancers. This review highlights the role of the approved tyrosine kinase receptor inhibitors for solid tumor therapy.https://www.jhsmr.org/index.php/jhsmr/article/view/557tyrosine kinase receptor inhibitormolecularly targeted therapytreatment, cancersolid tumor |
| spellingShingle | P Sunpaweravong Tyrosine kinase receptor inhibitor as a molecularly targeted therapy for solid tumors Journal of Health Science and Medical Research (JHSMR) tyrosine kinase receptor inhibitor molecularly targeted therapy treatment, cancer solid tumor |
| title | Tyrosine kinase receptor inhibitor as a molecularly targeted therapy for solid tumors |
| title_full | Tyrosine kinase receptor inhibitor as a molecularly targeted therapy for solid tumors |
| title_fullStr | Tyrosine kinase receptor inhibitor as a molecularly targeted therapy for solid tumors |
| title_full_unstemmed | Tyrosine kinase receptor inhibitor as a molecularly targeted therapy for solid tumors |
| title_short | Tyrosine kinase receptor inhibitor as a molecularly targeted therapy for solid tumors |
| title_sort | tyrosine kinase receptor inhibitor as a molecularly targeted therapy for solid tumors |
| topic | tyrosine kinase receptor inhibitor molecularly targeted therapy treatment, cancer solid tumor |
| url | https://www.jhsmr.org/index.php/jhsmr/article/view/557 |
| work_keys_str_mv | AT psunpaweravong tyrosinekinasereceptorinhibitorasamolecularlytargetedtherapyforsolidtumors |