Effect of Eight Weeks of Continuous Exercise and Resveratrol Supplementation on Insulin Resistance and Pyruvate Dehydrogenase Kinase 4 (PDK4) Expression in the Soleus Muscle of Elderly Diabetic Rats
Background and objectives: Pyruvate dehydrogenase kinase 4 (PDK4) is an enzyme involved in the regulation of glucose and fatty acid metabolism and homeostasis. The purpose of this study was to investigate effects of continuous exercise and resveratrol supplementation on insulin resistance and expres...
Main Authors: | ali salehi, hajar abaszadeh, parvin farzanegi |
---|---|
Format: | Article |
Language: | English |
Published: |
Golestan University of Medical Sciences
2019-07-01
|
Series: | Medical Laboratory Journal |
Subjects: | |
Online Access: | http://mlj.goums.ac.ir/article-1-1157-en.html |
Similar Items
-
Resveratrol Regulates Glucose and Lipid Metabolism in Diabetic Rats by Inhibition of PDK1/AKT Phosphorylation and HIF-1α Expression
by: Li S, et al.
Published: (2023-04-01) -
PDK4 dictates metabolic resistance to ferroptosis by suppressing pyruvate oxidation and fatty acid synthesis
by: Xinxin Song, et al.
Published: (2021-02-01) -
Inhibition of pyruvate dehydrogenase kinase improves carbohydrate utilization in Nile tilapia by regulating PDK2/4-PDHE1α axis and insulin sensitivity
by: Yuan Luo, et al.
Published: (2022-12-01) -
Fasting and Glucagon Stimulate Gene Expression of Pyruvate Dehydrogenase Kinase 4 in Chickens
by: Kazuhisa Honda, et al.
Published: (2017-10-01) -
Pyruvate Dehydrogenase Kinase 4 Deficiency Increases Tumorigenesis in a Murine Model of Bladder Cancer
by: Benjamin L. Woolbright, et al.
Published: (2023-03-01)