Case Report: Molecular Characterization of Aggressive Malignant Retroperitoneal Solitary Fibrous Tumor: A Case Study

Case Report: Molecular Characterization of Aggressive Malignant Retroperitoneal Solitary Fibrous Tumor: A Case Study

Solitary fibrous tumors (SFT) are mesenchymal neoplasms with a favorable prognosis usually originating from the visceral pleura. Rarely, they may occur at various extrapleural sites and show malignant behavior coupled with dedifferentiation. NAB2-STAT6 fusion gene and STAT6 nuclear expression are bi...

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Bibliographic Details
Main Authors: Haruna Nonaka, Shuya Kandori, Satoshi Nitta, Masanobu Shiga, Yoshiyuki Nagumo, Tomokazu Kimura, Takashi Kawahara, Hiromitsu Negoro, Akio Hoshi, Takahiro Kojima, Koji Kawai, Bryan J. Mathis, Takuro Tamura, Taka-Aki Sato, Mariko Yamato, Masayuki Noguchi, Hiroyuki Nishiyama
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Oncology
Subjects:
malignant solitary fibrous tumor
NAB2-STAT6 fusion gene
STAT6 nuclear expression
target DNA sequencing
TP53 mutation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.736969/full

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