LABORATORY CRITERIA OF WOUND READINESS FOR SKIN GRAFTING

Background. Objective tests to assess the effectiveness of chronic wound bed preparation (WBP) are laboratory studies, whose results will allow establishing the optimal timing of skin grafting (SG). Aim: To assess the diagnostic informative value of a set of laboratory indicators of the wound’s c...

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Main Author: Yarets Yu. I.
Format: Article
Language:Belarusian
Published: Grodno State Medical University 2017-12-01
Series:Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta
Subjects:
Online Access:http://journal-grsmu.by/index.php/ojs/article/view/2199/2018
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author Yarets Yu. I.
author_facet Yarets Yu. I.
author_sort Yarets Yu. I.
collection DOAJ
description Background. Objective tests to assess the effectiveness of chronic wound bed preparation (WBP) are laboratory studies, whose results will allow establishing the optimal timing of skin grafting (SG). Aim: To assess the diagnostic informative value of a set of laboratory indicators of the wound’s condition for determining the effectiveness of chronic WBP and establishing the wound readiness for SG. Material and Methods. The subjects of the study were 210 patients with chronic wounds. The results of their laboratory tests were compared depending on SG outcome: complete wound healing (75.3 % of the patients, n=158) or graft failure (24.7 %, n=52). Results. It was revealed that the use of a set of laboratory criteria of the wound’s condition allowed to assess the effectiveness of WBP and correctly determine the timing of SG in 97.8% of cases. The application of the criteria was based on their changes with respect to the cut-off values. For the convenience of interpreting the results, their scoring was introduced with the subsequent calculation of the formula. Conclusion. The informative criteria of the wound readiness for SG are the values of wound cytology, biofilm, functional activity of neutrophils.
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spelling doaj.art-57ce48e47c4a4ddda2e8f5c6a31d1ace2022-12-22T01:52:12ZbelGrodno State Medical UniversityŽurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta2221-87852413-01092017-12-0115554455010.25298/2221-8785-2017-15-5-544-550LABORATORY CRITERIA OF WOUND READINESS FOR SKIN GRAFTINGYarets Yu. I.0State Institution “Republican Scientific and Practical Centre for Radiation Medicine and Human Ecology”Background. Objective tests to assess the effectiveness of chronic wound bed preparation (WBP) are laboratory studies, whose results will allow establishing the optimal timing of skin grafting (SG). Aim: To assess the diagnostic informative value of a set of laboratory indicators of the wound’s condition for determining the effectiveness of chronic WBP and establishing the wound readiness for SG. Material and Methods. The subjects of the study were 210 patients with chronic wounds. The results of their laboratory tests were compared depending on SG outcome: complete wound healing (75.3 % of the patients, n=158) or graft failure (24.7 %, n=52). Results. It was revealed that the use of a set of laboratory criteria of the wound’s condition allowed to assess the effectiveness of WBP and correctly determine the timing of SG in 97.8% of cases. The application of the criteria was based on their changes with respect to the cut-off values. For the convenience of interpreting the results, their scoring was introduced with the subsequent calculation of the formula. Conclusion. The informative criteria of the wound readiness for SG are the values of wound cytology, biofilm, functional activity of neutrophils.http://journal-grsmu.by/index.php/ojs/article/view/2199/2018chronic woundskin graftingbiofilmwound cytologyfunctional activity of neutrophils.
spellingShingle Yarets Yu. I.
LABORATORY CRITERIA OF WOUND READINESS FOR SKIN GRAFTING
Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta
chronic wound
skin grafting
biofilm
wound cytology
functional activity of neutrophils.
title LABORATORY CRITERIA OF WOUND READINESS FOR SKIN GRAFTING
title_full LABORATORY CRITERIA OF WOUND READINESS FOR SKIN GRAFTING
title_fullStr LABORATORY CRITERIA OF WOUND READINESS FOR SKIN GRAFTING
title_full_unstemmed LABORATORY CRITERIA OF WOUND READINESS FOR SKIN GRAFTING
title_short LABORATORY CRITERIA OF WOUND READINESS FOR SKIN GRAFTING
title_sort laboratory criteria of wound readiness for skin grafting
topic chronic wound
skin grafting
biofilm
wound cytology
functional activity of neutrophils.
url http://journal-grsmu.by/index.php/ojs/article/view/2199/2018
work_keys_str_mv AT yaretsyui laboratorycriteriaofwoundreadinessforskingrafting