Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells.

Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells.

The 3-Deazaneplanocin A (DZNep), one of S-adenosylhomocysteine (AdoHcy) hydrolase inhibitors, has shown antitumor activities in a broad range of solid tumors and acute myeloid leukemia. Here, we examined its effects on multiple myeloma (MM) cells and found that, at 500 nM, it potently inhibited grow...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhigang Xie, Chonglei Bi, Lip Lee Cheong, Shaw Cheng Liu, Gaofeng Huang, Jianbiao Zhou, Qiang Yu, Chien-Shing Chen, Wee Joo Chng
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2011-01-01
Seri Bilgileri:PLoS ONE
Online Erişim:http://europepmc.org/articles/PMC3123372?pdf=render

Internet

http://europepmc.org/articles/PMC3123372?pdf=render

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