Clinical Relevance of Immersive Virtual Reality in the Assessment and Treatment of Addictive Disorders: A Systematic Review and Future Perspective

(1) Background: Virtual reality (VR) has been investigated in a variety of psychiatric disorders, including addictive disorders (ADs); (2) Objective: This systematic review evaluates the current evidence of immersive VR (using head-mounted displays) in the clinical assessment and treatment of ADs; (...

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Main Authors: Simon Langener, Joanne Van Der Nagel, Jeannette van Manen, Wiebren Markus, Boukje Dijkstra, Laura De Fuentes-Merillas, Randy Klaassen, Janika Heitmann, Dirk Heylen, Arnt Schellekens
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/10/16/3658
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author Simon Langener
Joanne Van Der Nagel
Jeannette van Manen
Wiebren Markus
Boukje Dijkstra
Laura De Fuentes-Merillas
Randy Klaassen
Janika Heitmann
Dirk Heylen
Arnt Schellekens
author_facet Simon Langener
Joanne Van Der Nagel
Jeannette van Manen
Wiebren Markus
Boukje Dijkstra
Laura De Fuentes-Merillas
Randy Klaassen
Janika Heitmann
Dirk Heylen
Arnt Schellekens
author_sort Simon Langener
collection DOAJ
description (1) Background: Virtual reality (VR) has been investigated in a variety of psychiatric disorders, including addictive disorders (ADs); (2) Objective: This systematic review evaluates the current evidence of immersive VR (using head-mounted displays) in the clinical assessment and treatment of ADs; (3) Method: PubMed and PsycINFO were queried for publications up to November 2020; (4) Results: We screened 4519 titles, 114 abstracts and 85 full-texts, and analyzed 36 articles regarding the clinical assessment (i.e., diagnostic and prognostic value; <i>n</i> = 19) and treatment (i.e., interventions; <i>n</i> = 17) of ADs. Though most VR assessment studies (<i>n</i> = 15/19) showed associations between VR-induced cue-reactivity and clinical parameters, only two studies specified diagnostic value. VR treatment studies based on exposure therapy showed no or negative effects. However, other VR interventions like embodied and aversive learning paradigms demonstrated positive findings. The overall study quality was rather poor; (5) Conclusion: Though VR in ADs provides ecologically valid environments to induce cue-reactivity and provide new treatment paradigms, the added clinical value in assessment and therapy remains to be elucidated before VR can be applied in clinical care. Therefore, future work should investigate VR efficacy in randomized clinical trials using well-defined clinical endpoints.
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spelling doaj.art-57d07a65b5424b5180c7dfe72980f56a2023-11-22T08:11:36ZengMDPI AGJournal of Clinical Medicine2077-03832021-08-011016365810.3390/jcm10163658Clinical Relevance of Immersive Virtual Reality in the Assessment and Treatment of Addictive Disorders: A Systematic Review and Future PerspectiveSimon Langener0Joanne Van Der Nagel1Jeannette van Manen2Wiebren Markus3Boukje Dijkstra4Laura De Fuentes-Merillas5Randy Klaassen6Janika Heitmann7Dirk Heylen8Arnt Schellekens9Human Media Interaction, University of Twente, 7522 NB Enschede, The NetherlandsHuman Media Interaction, University of Twente, 7522 NB Enschede, The NetherlandsTactus Addiction Centre, 7418 ET Deventer, The NetherlandsNijmegen Institute for Scientist-Practitioners in Addiction, 6525 GD Nijmegen, The NetherlandsNijmegen Institute for Scientist-Practitioners in Addiction, 6525 GD Nijmegen, The NetherlandsNijmegen Institute for Scientist-Practitioners in Addiction, 6525 GD Nijmegen, The NetherlandsHuman Media Interaction, University of Twente, 7522 NB Enschede, The NetherlandsNijmegen Institute for Scientist-Practitioners in Addiction, 6525 GD Nijmegen, The NetherlandsHuman Media Interaction, University of Twente, 7522 NB Enschede, The NetherlandsNijmegen Institute for Scientist-Practitioners in Addiction, 6525 GD Nijmegen, The Netherlands(1) Background: Virtual reality (VR) has been investigated in a variety of psychiatric disorders, including addictive disorders (ADs); (2) Objective: This systematic review evaluates the current evidence of immersive VR (using head-mounted displays) in the clinical assessment and treatment of ADs; (3) Method: PubMed and PsycINFO were queried for publications up to November 2020; (4) Results: We screened 4519 titles, 114 abstracts and 85 full-texts, and analyzed 36 articles regarding the clinical assessment (i.e., diagnostic and prognostic value; <i>n</i> = 19) and treatment (i.e., interventions; <i>n</i> = 17) of ADs. Though most VR assessment studies (<i>n</i> = 15/19) showed associations between VR-induced cue-reactivity and clinical parameters, only two studies specified diagnostic value. VR treatment studies based on exposure therapy showed no or negative effects. However, other VR interventions like embodied and aversive learning paradigms demonstrated positive findings. The overall study quality was rather poor; (5) Conclusion: Though VR in ADs provides ecologically valid environments to induce cue-reactivity and provide new treatment paradigms, the added clinical value in assessment and therapy remains to be elucidated before VR can be applied in clinical care. Therefore, future work should investigate VR efficacy in randomized clinical trials using well-defined clinical endpoints.https://www.mdpi.com/2077-0383/10/16/3658virtual realitysystematic reviewaddictionassessmenttreatmentcue-reactivity
spellingShingle Simon Langener
Joanne Van Der Nagel
Jeannette van Manen
Wiebren Markus
Boukje Dijkstra
Laura De Fuentes-Merillas
Randy Klaassen
Janika Heitmann
Dirk Heylen
Arnt Schellekens
Clinical Relevance of Immersive Virtual Reality in the Assessment and Treatment of Addictive Disorders: A Systematic Review and Future Perspective
Journal of Clinical Medicine
virtual reality
systematic review
addiction
assessment
treatment
cue-reactivity
title Clinical Relevance of Immersive Virtual Reality in the Assessment and Treatment of Addictive Disorders: A Systematic Review and Future Perspective
title_full Clinical Relevance of Immersive Virtual Reality in the Assessment and Treatment of Addictive Disorders: A Systematic Review and Future Perspective
title_fullStr Clinical Relevance of Immersive Virtual Reality in the Assessment and Treatment of Addictive Disorders: A Systematic Review and Future Perspective
title_full_unstemmed Clinical Relevance of Immersive Virtual Reality in the Assessment and Treatment of Addictive Disorders: A Systematic Review and Future Perspective
title_short Clinical Relevance of Immersive Virtual Reality in the Assessment and Treatment of Addictive Disorders: A Systematic Review and Future Perspective
title_sort clinical relevance of immersive virtual reality in the assessment and treatment of addictive disorders a systematic review and future perspective
topic virtual reality
systematic review
addiction
assessment
treatment
cue-reactivity
url https://www.mdpi.com/2077-0383/10/16/3658
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