The Structural, Functional and Evolutionary Impact of Transposable Elements in Eukaryotes
Transposable elements (TEs) are nearly ubiquitous in eukaryotes. The increase in genomic data, as well as progress in genome annotation and molecular biology techniques, have revealed the vast number of ways mobile elements have impacted the evolution of eukaryotes. In addition to being the main cau...
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| Format: | Article |
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MDPI AG
2021-06-01
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| Series: | Genes |
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| Online Access: | https://www.mdpi.com/2073-4425/12/6/918 |
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| author | Dareen Almojil Yann Bourgeois Marcin Falis Imtiyaz Hariyani Justin Wilcox Stéphane Boissinot |
| author_facet | Dareen Almojil Yann Bourgeois Marcin Falis Imtiyaz Hariyani Justin Wilcox Stéphane Boissinot |
| author_sort | Dareen Almojil |
| collection | DOAJ |
| description | Transposable elements (TEs) are nearly ubiquitous in eukaryotes. The increase in genomic data, as well as progress in genome annotation and molecular biology techniques, have revealed the vast number of ways mobile elements have impacted the evolution of eukaryotes. In addition to being the main cause of difference in haploid genome size, TEs have affected the overall organization of genomes by accumulating preferentially in some genomic regions, by causing structural rearrangements or by modifying the recombination rate. Although the vast majority of insertions is neutral or deleterious, TEs have been an important source of evolutionary novelties and have played a determinant role in the evolution of fundamental biological processes. TEs have been recruited in the regulation of host genes and are implicated in the evolution of regulatory networks. They have also served as a source of protein-coding sequences or even entire genes. The impact of TEs on eukaryotic evolution is only now being fully appreciated and the role they may play in a number of biological processes, such as speciation and adaptation, remains to be deciphered. |
| first_indexed | 2024-03-10T10:24:21Z |
| format | Article |
| id | doaj.art-57d2a4fe31c84ff2a30a0712178b560f |
| institution | Directory Open Access Journal |
| issn | 2073-4425 |
| language | English |
| last_indexed | 2024-03-10T10:24:21Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Genes |
| spelling | doaj.art-57d2a4fe31c84ff2a30a0712178b560f2023-11-22T00:07:45ZengMDPI AGGenes2073-44252021-06-0112691810.3390/genes12060918The Structural, Functional and Evolutionary Impact of Transposable Elements in EukaryotesDareen Almojil0Yann Bourgeois1Marcin Falis2Imtiyaz Hariyani3Justin Wilcox4Stéphane Boissinot5New York University Abu Dhabi, Saadiyat Island, Abu Dhabi P.O. Box 129188, United Arab EmiratesSchool of Biological Sciences, University of Portsmouth, Portsmouth, UKNew York University Abu Dhabi, Saadiyat Island, Abu Dhabi P.O. Box 129188, United Arab EmiratesNew York University Abu Dhabi, Saadiyat Island, Abu Dhabi P.O. Box 129188, United Arab EmiratesNew York University Abu Dhabi, Saadiyat Island, Abu Dhabi P.O. Box 129188, United Arab EmiratesNew York University Abu Dhabi, Saadiyat Island, Abu Dhabi P.O. Box 129188, United Arab EmiratesTransposable elements (TEs) are nearly ubiquitous in eukaryotes. The increase in genomic data, as well as progress in genome annotation and molecular biology techniques, have revealed the vast number of ways mobile elements have impacted the evolution of eukaryotes. In addition to being the main cause of difference in haploid genome size, TEs have affected the overall organization of genomes by accumulating preferentially in some genomic regions, by causing structural rearrangements or by modifying the recombination rate. Although the vast majority of insertions is neutral or deleterious, TEs have been an important source of evolutionary novelties and have played a determinant role in the evolution of fundamental biological processes. TEs have been recruited in the regulation of host genes and are implicated in the evolution of regulatory networks. They have also served as a source of protein-coding sequences or even entire genes. The impact of TEs on eukaryotic evolution is only now being fully appreciated and the role they may play in a number of biological processes, such as speciation and adaptation, remains to be deciphered.https://www.mdpi.com/2073-4425/12/6/918transposable elementsgenome evolutioneukaryotes |
| spellingShingle | Dareen Almojil Yann Bourgeois Marcin Falis Imtiyaz Hariyani Justin Wilcox Stéphane Boissinot The Structural, Functional and Evolutionary Impact of Transposable Elements in Eukaryotes Genes transposable elements genome evolution eukaryotes |
| title | The Structural, Functional and Evolutionary Impact of Transposable Elements in Eukaryotes |
| title_full | The Structural, Functional and Evolutionary Impact of Transposable Elements in Eukaryotes |
| title_fullStr | The Structural, Functional and Evolutionary Impact of Transposable Elements in Eukaryotes |
| title_full_unstemmed | The Structural, Functional and Evolutionary Impact of Transposable Elements in Eukaryotes |
| title_short | The Structural, Functional and Evolutionary Impact of Transposable Elements in Eukaryotes |
| title_sort | structural functional and evolutionary impact of transposable elements in eukaryotes |
| topic | transposable elements genome evolution eukaryotes |
| url | https://www.mdpi.com/2073-4425/12/6/918 |
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