Method and Application of Estimating Epidemiological Parameters Based on Data-Driven Approach

Determining initial variables and key parameters, such as case fatality ratio (CFR), dynamic case fatality ratio (DCFR), reproduction number (<inline-formula> <tex-math notation="LaTeX">$R_{0}$ </tex-math></inline-formula>), and so on, helps shed more light on the t...

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Main Authors: Yuqing Sun, Zhonghua Zhang, Gaochang Zhao
Format: Article
Language:English
Published: IEEE 2024-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/10360128/
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author Yuqing Sun
Zhonghua Zhang
Gaochang Zhao
author_facet Yuqing Sun
Zhonghua Zhang
Gaochang Zhao
author_sort Yuqing Sun
collection DOAJ
description Determining initial variables and key parameters, such as case fatality ratio (CFR), dynamic case fatality ratio (DCFR), reproduction number (<inline-formula> <tex-math notation="LaTeX">$R_{0}$ </tex-math></inline-formula>), and so on, helps shed more light on the transmission and control of emerging and re-emerging infectious diseases. Here, we established a SAIUHR model, which describes the dynamic changes of susceptible, asymptomatic infectious, under-reported symptomatic infectious, hospitalized and recovered individuals. And we proposed a novel approach based on our model to calculate the report rate, starting time, basic reproduction number, the initial conditions for the compartments, CFR and DCFR. Finally, we apply our method to epidemiological datasets from China, Italy, Germany, and France. The results show that the goodness of fit for the cumulative confirmed cases is greater than 97.45&#x0025; in each of the countries, DCFR is more effective than CFR in predicting the future tend of infectious disease, and improving the report rate, raising the control strength and shortening the wait time are the effective strategies against infectious diseases. This study highlights the implications of taking proper restrictions and strong policies to deal with emerging and re-emerging infectious diseases from their spread in the early stage.
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spelling doaj.art-57d340084cb44e5e913f260cda6e139d2024-02-08T00:02:15ZengIEEEIEEE Access2169-35362024-01-0112180121802010.1109/ACCESS.2023.334292010360128Method and Application of Estimating Epidemiological Parameters Based on Data-Driven ApproachYuqing Sun0https://orcid.org/0009-0005-8748-4064Zhonghua Zhang1Gaochang Zhao2School of Science, Xi&#x2019;an University of Science and Technology, Xi&#x2019;an, ChinaSchool of Science, Xi&#x2019;an University of Science and Technology, Xi&#x2019;an, ChinaSchool of Science, Xi&#x2019;an University of Science and Technology, Xi&#x2019;an, ChinaDetermining initial variables and key parameters, such as case fatality ratio (CFR), dynamic case fatality ratio (DCFR), reproduction number (<inline-formula> <tex-math notation="LaTeX">$R_{0}$ </tex-math></inline-formula>), and so on, helps shed more light on the transmission and control of emerging and re-emerging infectious diseases. Here, we established a SAIUHR model, which describes the dynamic changes of susceptible, asymptomatic infectious, under-reported symptomatic infectious, hospitalized and recovered individuals. And we proposed a novel approach based on our model to calculate the report rate, starting time, basic reproduction number, the initial conditions for the compartments, CFR and DCFR. Finally, we apply our method to epidemiological datasets from China, Italy, Germany, and France. The results show that the goodness of fit for the cumulative confirmed cases is greater than 97.45&#x0025; in each of the countries, DCFR is more effective than CFR in predicting the future tend of infectious disease, and improving the report rate, raising the control strength and shortening the wait time are the effective strategies against infectious diseases. This study highlights the implications of taking proper restrictions and strong policies to deal with emerging and re-emerging infectious diseases from their spread in the early stage.https://ieeexplore.ieee.org/document/10360128/Basic reproduction numberdata-drivenepidemic modelparameter estimation
spellingShingle Yuqing Sun
Zhonghua Zhang
Gaochang Zhao
Method and Application of Estimating Epidemiological Parameters Based on Data-Driven Approach
IEEE Access
Basic reproduction number
data-driven
epidemic model
parameter estimation
title Method and Application of Estimating Epidemiological Parameters Based on Data-Driven Approach
title_full Method and Application of Estimating Epidemiological Parameters Based on Data-Driven Approach
title_fullStr Method and Application of Estimating Epidemiological Parameters Based on Data-Driven Approach
title_full_unstemmed Method and Application of Estimating Epidemiological Parameters Based on Data-Driven Approach
title_short Method and Application of Estimating Epidemiological Parameters Based on Data-Driven Approach
title_sort method and application of estimating epidemiological parameters based on data driven approach
topic Basic reproduction number
data-driven
epidemic model
parameter estimation
url https://ieeexplore.ieee.org/document/10360128/
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AT zhonghuazhang methodandapplicationofestimatingepidemiologicalparametersbasedondatadrivenapproach
AT gaochangzhao methodandapplicationofestimatingepidemiologicalparametersbasedondatadrivenapproach