Current trends of high-risk gene Cul3 in neurodevelopmental disorders

Current trends of high-risk gene Cul3 in neurodevelopmental disorders

Cul3 encodes Cullin-3, a core component of the ubiquitin E3 ligase that is involved in protein ubiquitination. Recent studies have identified Cul3 as a high-confidence risk gene in neurodevelopmental disorders (NDDs), especially autism spectrum disorder (ASD). Different strategies have been used to...

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Bibliographic Details
Main Authors:	Ping Lin, Jie Yang, Shumin Wu, Tong Ye, Wenting Zhuang, Wei Wang, Tao Tan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-07-01
Series:	Frontiers in Psychiatry
Subjects:	Cul3 Cullin3-RING E3 ubiquitin ligases neurodevelopmental disorders (NDDs) autism spectrum disorder (ASD) knockout (KO) mice
Online Access:	https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1215110/full

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