PNMA5 Promotes Bone Metastasis of Non-small-Cell Lung Cancer as a Target of BMP2 Signaling

PNMA5 Promotes Bone Metastasis of Non-small-Cell Lung Cancer as a Target of BMP2 Signaling

Bone metastases frequently occur in NSCLC patients at the late stage, indicating poor survival. However, mechanisms about the initiation of NSCLC bone metastases remain largely unclear. In our previous reports, BMP2 signaling activation has been found to enhance NSCLC bone metastases through enhanci...

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Bibliographic Details
Main Authors: Fei Huang, Yaqiang Cao, Caihong Wang, Ruilong Lan, Bing Wu, Xianhe Xie, Jinsheng Hong, Lengxi Fu, Gui Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
PNMA5
NSCLC
bone metastases
BMP2
target gene
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.678931/full

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