Use of a glycolipid inhibitor to ameliorate renal cancer in a mouse model.
In a xenograft model wherein, live renal cancer cells were implanted under the kidney capsule in mice, revealed a 30-fold increase in tumor volume over a period of 26 days and this was accompanied with a 32-fold increase in the level of lactosylceramide (LacCer). Mice fed D- threo-1-phenyl-2-decanoy...
Главные авторы: | Subroto Chatterjee, Nezar Alsaeedi, Jennifer Hou, Veera Venkata Ratnam Bandaru, Lan Wu, Marc K Halushka, Roberto Pili, Georges Ndikuyeze, Norman J Haughey |
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Формат: | Статья |
Язык: | English |
Опубликовано: |
Public Library of Science (PLoS)
2013-01-01
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Серии: | PLoS ONE |
Online-ссылка: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23671696/?tool=EBI |
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