Use of a glycolipid inhibitor to ameliorate renal cancer in a mouse model.

In a xenograft model wherein, live renal cancer cells were implanted under the kidney capsule in mice, revealed a 30-fold increase in tumor volume over a period of 26 days and this was accompanied with a 32-fold increase in the level of lactosylceramide (LacCer). Mice fed D- threo-1-phenyl-2-decanoy...

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Main Authors: Subroto Chatterjee, Nezar Alsaeedi, Jennifer Hou, Veera Venkata Ratnam Bandaru, Lan Wu, Marc K Halushka, Roberto Pili, Georges Ndikuyeze, Norman J Haughey
格式: Article
語言:English
出版: Public Library of Science (PLoS) 2013-01-01
叢編:PLoS ONE
在線閱讀:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23671696/?tool=EBI