Inter-species geographic signatures for tracing horizontal gene transfer and long-term persistence of carbapenem resistance

Inter-species geographic signatures for tracing horizontal gene transfer and long-term persistence of carbapenem resistance

Abstract Background Carbapenem-resistant Enterobacterales (CRE) are an urgent global health threat. Inferring the dynamics of local CRE dissemination is currently limited by our inability to confidently trace the spread of resistance determinants to unrelated bacterial hosts. Whole-genome sequence c...

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Bibliographic Details
Main Authors: Rauf Salamzade, Abigail L. Manson, Bruce J. Walker, Thea Brennan-Krohn, Colin J. Worby, Peijun Ma, Lorrie L. He, Terrance P. Shea, James Qu, Sinéad B. Chapman, Whitney Howe, Sarah K. Young, Jenna I. Wurster, Mary L. Delaney, Sanjat Kanjilal, Andrew B. Onderdonk, Cassiana E. Bittencourt, Gabrielle M. Gussin, Diane Kim, Ellena M. Peterson, Mary Jane Ferraro, David C. Hooper, Erica S. Shenoy, Christina A. Cuomo, Lisa A. Cosimi, Susan S. Huang, James E. Kirby, Virginia M. Pierce, Roby P. Bhattacharyya, Ashlee M. Earl
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Genome Medicine
Online Access:https://doi.org/10.1186/s13073-022-01040-y

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https://doi.org/10.1186/s13073-022-01040-y

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