Atrial fibrillation incidence and outcomes in two cohorts of octogenarians: LiLACS NZ
Abstract Background Atrial fibrillation (AF), the most common cardiac arrhythmia in the general population, has significant healthcare burden. Little is known about AF in octogenarians. Objective To describe the prevalence and incidence rate of AF in New Zealand (NZ) octogenarians and the risk of st...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-03-01
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| Series: | BMC Geriatrics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12877-023-03902-5 |
| _version_ | 1797853581680836608 |
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| author | Ruth Teh Ngaire Kerse Avinesh Pillai Thomas Lumley Anna Rolleston Tin Aung Kyaw Martin Connolly Joanna Broad Elaine Monteiro Valerie Wright-St Clair Robert N. Doughty |
| author_facet | Ruth Teh Ngaire Kerse Avinesh Pillai Thomas Lumley Anna Rolleston Tin Aung Kyaw Martin Connolly Joanna Broad Elaine Monteiro Valerie Wright-St Clair Robert N. Doughty |
| author_sort | Ruth Teh |
| collection | DOAJ |
| description | Abstract Background Atrial fibrillation (AF), the most common cardiac arrhythmia in the general population, has significant healthcare burden. Little is known about AF in octogenarians. Objective To describe the prevalence and incidence rate of AF in New Zealand (NZ) octogenarians and the risk of stroke and mortality at 5-year follow-up. Design Longitudinal Cohort Study. Setting Bay of Plenty and Lakes health regions of New Zealand. Subjects Eight-hundred-seventy-seven (379 indigenous Māori, 498 non-Māori) were included in the analysis. Methods AF, stroke/TIA events and relevant co-variates were established annually using self-report and hospital records (and ECG for AF). Cox proportional-hazards regression models were used to determine the time dependent AF risk of stroke/TIA. Results AF was present in 21% at baseline (Māori 26%, non-Māori 18%), the prevalence doubled over 5-years (Māori 50%, non-Māori 33%). 5-year AF incidence was 82.6 /1000-person years and at all times AF incidence for Māori was twice that of non-Māori. Five-year stroke/TIA prevalence was 23% (22% in Māori and 24% non- Māori), higher in those with AF than without. AF was not independently associated with 5-year new stroke/TIA; baseline systolic blood pressure was. Mortality was higher for Māori, men, those with AF and CHF and statin use was protective. In summary, AF is more prevalent in indigenous octogenarians and should have an increased focus in health care management. Further research could examine treatment in more detail to facilitate ethnic specific impact and risks and benefits of treating AF in octogenarians. |
| first_indexed | 2024-04-09T19:52:58Z |
| format | Article |
| id | doaj.art-57e0ddc3276f4b7198ed17d8bca90aa0 |
| institution | Directory Open Access Journal |
| issn | 1471-2318 |
| language | English |
| last_indexed | 2024-04-09T19:52:58Z |
| publishDate | 2023-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Geriatrics |
| spelling | doaj.art-57e0ddc3276f4b7198ed17d8bca90aa02023-04-03T05:40:10ZengBMCBMC Geriatrics1471-23182023-03-0123111110.1186/s12877-023-03902-5Atrial fibrillation incidence and outcomes in two cohorts of octogenarians: LiLACS NZRuth Teh0Ngaire Kerse1Avinesh Pillai2Thomas Lumley3Anna Rolleston4Tin Aung Kyaw5Martin Connolly6Joanna Broad7Elaine Monteiro8Valerie Wright-St Clair9Robert N. Doughty10Department of General Practice and Primary Health Care, Faculty of Medical and Health Sciences, University of AucklandDepartment of General Practice and Primary Health Care, Faculty of Medical and Health Sciences, University of AucklandDepartment of Statistics, Faculty of Science, University of AucklandDepartment of Statistics, Faculty of Science, University of AucklandManawa Ora, The Centre for HealthDepartment of General Practice and Primary Health Care, Faculty of Medical and Health Sciences, University of AucklandDepartment of Geriatric Medicine, Faculty of Medical and Health Sciences, University of AucklandDepartment of Geriatric Medicine, Faculty of Medical and Health Sciences, University of AucklandDepartment of General Practice and Primary Health Care, Faculty of Medical and Health Sciences, University of AucklandCentre for Active Ageing, Auckland University of Technology New ZealandDepartment of Medicine, University of Auckland and Greenlane Cardiovascular Service, Auckland District Health BoardAbstract Background Atrial fibrillation (AF), the most common cardiac arrhythmia in the general population, has significant healthcare burden. Little is known about AF in octogenarians. Objective To describe the prevalence and incidence rate of AF in New Zealand (NZ) octogenarians and the risk of stroke and mortality at 5-year follow-up. Design Longitudinal Cohort Study. Setting Bay of Plenty and Lakes health regions of New Zealand. Subjects Eight-hundred-seventy-seven (379 indigenous Māori, 498 non-Māori) were included in the analysis. Methods AF, stroke/TIA events and relevant co-variates were established annually using self-report and hospital records (and ECG for AF). Cox proportional-hazards regression models were used to determine the time dependent AF risk of stroke/TIA. Results AF was present in 21% at baseline (Māori 26%, non-Māori 18%), the prevalence doubled over 5-years (Māori 50%, non-Māori 33%). 5-year AF incidence was 82.6 /1000-person years and at all times AF incidence for Māori was twice that of non-Māori. Five-year stroke/TIA prevalence was 23% (22% in Māori and 24% non- Māori), higher in those with AF than without. AF was not independently associated with 5-year new stroke/TIA; baseline systolic blood pressure was. Mortality was higher for Māori, men, those with AF and CHF and statin use was protective. In summary, AF is more prevalent in indigenous octogenarians and should have an increased focus in health care management. Further research could examine treatment in more detail to facilitate ethnic specific impact and risks and benefits of treating AF in octogenarians.https://doi.org/10.1186/s12877-023-03902-5Atrial FibrillationOctogenariansIndigenous Peoples |
| spellingShingle | Ruth Teh Ngaire Kerse Avinesh Pillai Thomas Lumley Anna Rolleston Tin Aung Kyaw Martin Connolly Joanna Broad Elaine Monteiro Valerie Wright-St Clair Robert N. Doughty Atrial fibrillation incidence and outcomes in two cohorts of octogenarians: LiLACS NZ BMC Geriatrics Atrial Fibrillation Octogenarians Indigenous Peoples |
| title | Atrial fibrillation incidence and outcomes in two cohorts of octogenarians: LiLACS NZ |
| title_full | Atrial fibrillation incidence and outcomes in two cohorts of octogenarians: LiLACS NZ |
| title_fullStr | Atrial fibrillation incidence and outcomes in two cohorts of octogenarians: LiLACS NZ |
| title_full_unstemmed | Atrial fibrillation incidence and outcomes in two cohorts of octogenarians: LiLACS NZ |
| title_short | Atrial fibrillation incidence and outcomes in two cohorts of octogenarians: LiLACS NZ |
| title_sort | atrial fibrillation incidence and outcomes in two cohorts of octogenarians lilacs nz |
| topic | Atrial Fibrillation Octogenarians Indigenous Peoples |
| url | https://doi.org/10.1186/s12877-023-03902-5 |
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