Preparation and evaluation of clove oil in emu oil self-emulsion for hair conditioning and hair loss prevention
Introduction: From a consumer perspective, developing a hair care formulation that offers multi-purpose products to enhance routine hair care such as conditioning, cleaning and grooming hair and stimulating hair follicles is important. Eugenol comprising about 70% of clove essential oil shows an and...
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| Format: | Article |
| Language: | English |
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Shahrekord University of Medical Sciences
2016-03-01
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| Series: | Journal of HerbMed Pharmacology |
| Subjects: | |
| Online Access: | http://herbmedpharmacol.com/PDF/JHP_20160324165939 |
| _version_ | 1798019135180898304 |
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| author | Mohammad Ali Shahtalebi Atefeh Sadat-Hosseini Leila Safaeian |
| author_facet | Mohammad Ali Shahtalebi Atefeh Sadat-Hosseini Leila Safaeian |
| author_sort | Mohammad Ali Shahtalebi |
| collection | DOAJ |
| description | Introduction: From a consumer perspective, developing a hair care formulation that offers multi-purpose products to enhance routine hair care such as conditioning, cleaning and grooming hair and stimulating hair follicles is important. Eugenol comprising about 70% of clove essential oil shows an androgenic activity and stimulates hair root to feed and hence could be a good candidate for developing an anti-hair loss formulation. Thus in hair research, hair follicle is of great interest. The aim of this study was to develop a self-emulsifying product containing eugenol in emu oil as a carrier.Methods: Eugenol was identified in clove oil extraction by UV spectrophotometer. Emu oil was characterized according to national oil standards. All formulations were prepared and best one was selected for further pharmaceutical examinations such as pH, particle size, content uniformity and drug release. The optimum formulation was clinically evaluated on rats back compared with minoxidil standard lotion as a positive control and distilled water as a negative control.Results: The selected formulation was demonstrated to condition hair with grooming and enhanced hair growth with longer lag time compared with minoxidil but after one week the hair growth accelerated.Conclusion: The formulation containing clove oil in emu oil self-emulsion shows a conditioning and grooming property with hair shaft repair and hair growth. |
| first_indexed | 2024-04-11T16:35:51Z |
| format | Article |
| id | doaj.art-57e172e9492f47239a21072a74c2cff3 |
| institution | Directory Open Access Journal |
| issn | 2345-5004 |
| language | English |
| last_indexed | 2024-04-11T16:35:51Z |
| publishDate | 2016-03-01 |
| publisher | Shahrekord University of Medical Sciences |
| record_format | Article |
| series | Journal of HerbMed Pharmacology |
| spelling | doaj.art-57e172e9492f47239a21072a74c2cff32022-12-22T04:13:51ZengShahrekord University of Medical SciencesJournal of HerbMed Pharmacology2345-50042016-03-01527277JHP_20160324165939Preparation and evaluation of clove oil in emu oil self-emulsion for hair conditioning and hair loss preventionMohammad Ali Shahtalebi0Atefeh Sadat-Hosseini1Leila Safaeian2Department of Pharmaceutics, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, IranStudent Research Committee, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, IranDepartment of Pharmaceutical Pharmacology, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, IranIntroduction: From a consumer perspective, developing a hair care formulation that offers multi-purpose products to enhance routine hair care such as conditioning, cleaning and grooming hair and stimulating hair follicles is important. Eugenol comprising about 70% of clove essential oil shows an androgenic activity and stimulates hair root to feed and hence could be a good candidate for developing an anti-hair loss formulation. Thus in hair research, hair follicle is of great interest. The aim of this study was to develop a self-emulsifying product containing eugenol in emu oil as a carrier.Methods: Eugenol was identified in clove oil extraction by UV spectrophotometer. Emu oil was characterized according to national oil standards. All formulations were prepared and best one was selected for further pharmaceutical examinations such as pH, particle size, content uniformity and drug release. The optimum formulation was clinically evaluated on rats back compared with minoxidil standard lotion as a positive control and distilled water as a negative control.Results: The selected formulation was demonstrated to condition hair with grooming and enhanced hair growth with longer lag time compared with minoxidil but after one week the hair growth accelerated.Conclusion: The formulation containing clove oil in emu oil self-emulsion shows a conditioning and grooming property with hair shaft repair and hair growth.http://herbmedpharmacol.com/PDF/JHP_20160324165939Hair lossEugenolEmu oilConditioner |
| spellingShingle | Mohammad Ali Shahtalebi Atefeh Sadat-Hosseini Leila Safaeian Preparation and evaluation of clove oil in emu oil self-emulsion for hair conditioning and hair loss prevention Journal of HerbMed Pharmacology Hair loss Eugenol Emu oil Conditioner |
| title | Preparation and evaluation of clove oil in emu oil self-emulsion for hair conditioning and hair loss prevention |
| title_full | Preparation and evaluation of clove oil in emu oil self-emulsion for hair conditioning and hair loss prevention |
| title_fullStr | Preparation and evaluation of clove oil in emu oil self-emulsion for hair conditioning and hair loss prevention |
| title_full_unstemmed | Preparation and evaluation of clove oil in emu oil self-emulsion for hair conditioning and hair loss prevention |
| title_short | Preparation and evaluation of clove oil in emu oil self-emulsion for hair conditioning and hair loss prevention |
| title_sort | preparation and evaluation of clove oil in emu oil self emulsion for hair conditioning and hair loss prevention |
| topic | Hair loss Eugenol Emu oil Conditioner |
| url | http://herbmedpharmacol.com/PDF/JHP_20160324165939 |
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