Viral Transmission and Clinical Features in Asymptomatic Carriers of SARS-CoV-2 in Wuhan, China
We report the clinical characteristics, viral shedding duration, and contact tracing for asymptomatic carriers of SARS-CoV-2 in Wuhan, China. The asymptomatic carriers were relatively young (median age: 34.5 years). Chest computed tomography showed no abnormalities. The nasopharyngeal swab was an op...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-08-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fmed.2020.00547/full |
| _version_ | 1818175419482898432 |
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| author | Fen Tan Kaige Wang Jiasheng Liu Dan Liu Jianfei Luo Rui Zhou |
| author_facet | Fen Tan Kaige Wang Jiasheng Liu Dan Liu Jianfei Luo Rui Zhou |
| author_sort | Fen Tan |
| collection | DOAJ |
| description | We report the clinical characteristics, viral shedding duration, and contact tracing for asymptomatic carriers of SARS-CoV-2 in Wuhan, China. The asymptomatic carriers were relatively young (median age: 34.5 years). Chest computed tomography showed no abnormalities. The nasopharyngeal swab was an optimum specimen for RNA testing. The median viral shedding duration was 11.5 days. Notably, 2 months of viral shedding duration were reported in two nurses, which was much longer than previously reported or than usually thought. The transmissibility of SARS-CoV-2 by asymptomatic carriers during the studied period in Wuhan appeared to be weak. Only one patient (1/12) was found to have transmitted the virus to another person. Early asymptomatic carrier detection, isolation, and contact tracing could be useful to mitigate the spread of the disease. |
| first_indexed | 2024-12-11T20:00:00Z |
| format | Article |
| id | doaj.art-57e1fd542cd7415a8eff3ec5d6b5bff7 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-12-11T20:00:00Z |
| publishDate | 2020-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-57e1fd542cd7415a8eff3ec5d6b5bff72022-12-22T00:52:33ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2020-08-01710.3389/fmed.2020.00547554707Viral Transmission and Clinical Features in Asymptomatic Carriers of SARS-CoV-2 in Wuhan, ChinaFen Tan0Kaige Wang1Jiasheng Liu2Dan Liu3Jianfei Luo4Rui Zhou5Department of Pulmonary and Critical Care Medicine, The Second Xiangya Hospital, Respiratory Disease Research Institute of Hunan Province, Central South University, Changsha, ChinaDepartment of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan, ChinaDepartment of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan, ChinaDepartment of Pulmonary and Critical Care Medicine, The Second Xiangya Hospital, Respiratory Disease Research Institute of Hunan Province, Central South University, Changsha, ChinaWe report the clinical characteristics, viral shedding duration, and contact tracing for asymptomatic carriers of SARS-CoV-2 in Wuhan, China. The asymptomatic carriers were relatively young (median age: 34.5 years). Chest computed tomography showed no abnormalities. The nasopharyngeal swab was an optimum specimen for RNA testing. The median viral shedding duration was 11.5 days. Notably, 2 months of viral shedding duration were reported in two nurses, which was much longer than previously reported or than usually thought. The transmissibility of SARS-CoV-2 by asymptomatic carriers during the studied period in Wuhan appeared to be weak. Only one patient (1/12) was found to have transmitted the virus to another person. Early asymptomatic carrier detection, isolation, and contact tracing could be useful to mitigate the spread of the disease.https://www.frontiersin.org/article/10.3389/fmed.2020.00547/fullSARS-CoV-2COVID-19asymptomatic carriertransmission abilityclinical features |
| spellingShingle | Fen Tan Kaige Wang Jiasheng Liu Dan Liu Jianfei Luo Rui Zhou Viral Transmission and Clinical Features in Asymptomatic Carriers of SARS-CoV-2 in Wuhan, China Frontiers in Medicine SARS-CoV-2 COVID-19 asymptomatic carrier transmission ability clinical features |
| title | Viral Transmission and Clinical Features in Asymptomatic Carriers of SARS-CoV-2 in Wuhan, China |
| title_full | Viral Transmission and Clinical Features in Asymptomatic Carriers of SARS-CoV-2 in Wuhan, China |
| title_fullStr | Viral Transmission and Clinical Features in Asymptomatic Carriers of SARS-CoV-2 in Wuhan, China |
| title_full_unstemmed | Viral Transmission and Clinical Features in Asymptomatic Carriers of SARS-CoV-2 in Wuhan, China |
| title_short | Viral Transmission and Clinical Features in Asymptomatic Carriers of SARS-CoV-2 in Wuhan, China |
| title_sort | viral transmission and clinical features in asymptomatic carriers of sars cov 2 in wuhan china |
| topic | SARS-CoV-2 COVID-19 asymptomatic carrier transmission ability clinical features |
| url | https://www.frontiersin.org/article/10.3389/fmed.2020.00547/full |
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