Clostridium septicum sepsis and colorectal cancer - a reminder
<p>Abstract</p> <p>Background</p> <p>Spontaneous clostridium septicum infections are rare and are associated with a high mortality. Association of clostridium infection with colorectal malignancies have been previously reported and most cases are described in tumours of...
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| Format: | Article |
| Language: | English |
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BMC
2009-10-01
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| Series: | World Journal of Surgical Oncology |
| Online Access: | http://www.wjso.com/content/7/1/73 |
| _version_ | 1811250908279865344 |
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| author | McCloud Jonathon M Mirza Nazzia N Cheetham Mark J |
| author_facet | McCloud Jonathon M Mirza Nazzia N Cheetham Mark J |
| author_sort | McCloud Jonathon M |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Spontaneous clostridium septicum infections are rare and are associated with a high mortality. Association of clostridium infection with colorectal malignancies have been previously reported and most cases are described in tumours of the ascending colon. We report our experience of clostridium septicum infection in the presence of tumour perforation in a series of two patients as a reminder of its association with sepsis in the presence of colorectal malignancy.</p> <p>Case Presentation</p> <p>We isolated clostridium septicum infection in a series of two patients admitted as emergencies. One patient was found to have a perforated caecal tumour intraoperatively whilst the other had a perforated rectal tumour. The clinical outcome and management of each case are reported and underlying reasons for variations in outcome are discussed.</p> <p>Conclusion</p> <p>Although uncomman, the possibility of clostridium septicum sepsis should be borne in mind in patients who present with underlying malignancy and have sepsis. The cumulative effect of sepsis and malignant perforation is associated with a high morbidity and mortality. Awareness and early diagnosis of clostridium septicum may improve the prognosis of what is usually regarded as a fatal infection.</p> |
| first_indexed | 2024-04-12T16:11:47Z |
| format | Article |
| id | doaj.art-57e44d73a9bd45b783efc132f6a88595 |
| institution | Directory Open Access Journal |
| issn | 1477-7819 |
| language | English |
| last_indexed | 2024-04-12T16:11:47Z |
| publishDate | 2009-10-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj.art-57e44d73a9bd45b783efc132f6a885952022-12-22T03:25:52ZengBMCWorld Journal of Surgical Oncology1477-78192009-10-01717310.1186/1477-7819-7-73Clostridium septicum sepsis and colorectal cancer - a reminderMcCloud Jonathon MMirza Nazzia NCheetham Mark J<p>Abstract</p> <p>Background</p> <p>Spontaneous clostridium septicum infections are rare and are associated with a high mortality. Association of clostridium infection with colorectal malignancies have been previously reported and most cases are described in tumours of the ascending colon. We report our experience of clostridium septicum infection in the presence of tumour perforation in a series of two patients as a reminder of its association with sepsis in the presence of colorectal malignancy.</p> <p>Case Presentation</p> <p>We isolated clostridium septicum infection in a series of two patients admitted as emergencies. One patient was found to have a perforated caecal tumour intraoperatively whilst the other had a perforated rectal tumour. The clinical outcome and management of each case are reported and underlying reasons for variations in outcome are discussed.</p> <p>Conclusion</p> <p>Although uncomman, the possibility of clostridium septicum sepsis should be borne in mind in patients who present with underlying malignancy and have sepsis. The cumulative effect of sepsis and malignant perforation is associated with a high morbidity and mortality. Awareness and early diagnosis of clostridium septicum may improve the prognosis of what is usually regarded as a fatal infection.</p>http://www.wjso.com/content/7/1/73 |
| spellingShingle | McCloud Jonathon M Mirza Nazzia N Cheetham Mark J Clostridium septicum sepsis and colorectal cancer - a reminder World Journal of Surgical Oncology |
| title | Clostridium septicum sepsis and colorectal cancer - a reminder |
| title_full | Clostridium septicum sepsis and colorectal cancer - a reminder |
| title_fullStr | Clostridium septicum sepsis and colorectal cancer - a reminder |
| title_full_unstemmed | Clostridium septicum sepsis and colorectal cancer - a reminder |
| title_short | Clostridium septicum sepsis and colorectal cancer - a reminder |
| title_sort | clostridium septicum sepsis and colorectal cancer a reminder |
| url | http://www.wjso.com/content/7/1/73 |
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