Hydrogen gas inhalation ameliorates LPS-induced BPD by inhibiting inflammation via regulating the TLR4–NFκB–IL6/NLRP3 signaling pathway in the placenta

Hydrogen gas inhalation ameliorates LPS-induced BPD by inhibiting inflammation via regulating the TLR4–NFκB–IL6/NLRP3 signaling pathway in the placenta

Abstract Introduction Hydrogen (H2) is regarded as a novel therapeutic agent against several diseases owing to its inherent biosafety. Bronchopulmonary dysplasia (BPD) has been widely considered among adverse pregnancy outcomes, without effective treatment. Placenta plays a role in defense, synthesi...

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Hlavní autoři: Yafang Zhang, Xianhui Ren, Linli Zhang, Xinliu Sun, Wenjing Li, Yunxi Chen, Yan Tian, Zhongxia Chu, Youzhen Wei, Guo Yao, Yan Wang
Médium: Článek
Jazyk:English
Vydáno: BMC 2024-05-01
Edice:European Journal of Medical Research
Témata:
Hydrogen
BPD
Placenta
Inflammation
TLR4
NFκB
On-line přístup:https://doi.org/10.1186/s40001-024-01874-9

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