Effect of an Eight-week High-intensity Interval Training Program on Serum Cardiac Troponin I Level of Streptozotocin-induced Diabetic Rats
Background One of the complications of diabetes, as a chronic metabolic disorder, is cardiovascular diseases. Objective This study aims to investigate the effect of an eight-week High-Intensity Interval Training (HIIT) program on serum Cardiac troponin I (CtnI) level in streptozotocin-induced diab...
| Main Authors: | , , |
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| Format: | Article |
| Language: | fas |
| Published: |
Qazvin University of Medical Sciences & Health Services
2021-01-01
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| Series: | The Journal of Qazvin University of Medical Sciences |
| Subjects: | |
| Online Access: | http://journal.qums.ac.ir/article-1-3092-en.html |
| Summary: | Background One of the complications of diabetes, as a chronic metabolic disorder, is cardiovascular diseases.
Objective This study aims to investigate the effect of an eight-week High-Intensity Interval Training (HIIT)
program on serum Cardiac troponin I (CtnI) level in streptozotocin-induced diabetic rats.
Methods In this experimental clinical trial, 30 rats were randomly assigned into three groups of healthy
Control (C), Diabetic (D), and diabetic+training (D+T). The third group performed the training which included
a treadmill running at an intensity of 85%-90% of maximum speed in 6-12 sessions of 2 min for 8
weeks, 5 days per week. Blood glucose level and high-sensitive CtnI levels were measured 48 hours after
the last training session and 12 hours of fasting. One-way ANOVA and Tukey’s test were used to analyze
the collected data, considering a significance level of P<0.05.
Findings The induction of diabetes caused a significant increase in blood glucose (P=0.01) and high-sensitive
CtnI (P=0.01) levels in the D group. Also, a significant difference was observed in the blood glucose
level of D+T group compared to the D group (P=0.001). The CtnI level also slightly reduced (11%) in the
D+T group compared to the D group, but it was not statistically significant (P=0.591).
Conclusion he HIIT program can reduce the fasting blood glucose and increase the serum level of highsensitive
CtnI to some extent in diabetic rats; therefore, it can be an appropriate strategy for diabetics.
However, there is a need for more studies in this area. |
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| ISSN: | 1561-3666 2228-7213 |