The diagnostic accuracy of ultrasonography versus endoscopy for primary nasopharyngeal carcinoma.
OBJECTIVE:To compare the accuracy of ultrasonography (US) with the current clinical standard of endoscopy for a diagnosis of nasopharyngeal carcinoma (NPC). METHODS:A total of 150 patients suspected of having NPC underwent US and endoscopy. A diagnosis was obtained from an endoscopic biopsy collecte...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3940890?pdf=render |
| _version_ | 1811207548755247104 |
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| author | Yong Gao Jun-Jie Liu Shang-Yong Zhu Xiang Yi |
| author_facet | Yong Gao Jun-Jie Liu Shang-Yong Zhu Xiang Yi |
| author_sort | Yong Gao |
| collection | DOAJ |
| description | OBJECTIVE:To compare the accuracy of ultrasonography (US) with the current clinical standard of endoscopy for a diagnosis of nasopharyngeal carcinoma (NPC). METHODS:A total of 150 patients suspected of having NPC underwent US and endoscopy. A diagnosis was obtained from an endoscopic biopsy collected from each suspected tumor and was compared with a biopsy obtained from a normal nasopharynx. The diagnostic accuracy of US and endoscopy for NPC was evaluated using receiver operating curve (ROC) analysis performed by MedCalc Software. RESULTS:The sensitivity, specificity, and accuracy of US versus endoscopy for this cohort were 90.1%, 84.8%, and 87.3% for US, and 88.7%, 97.5%, and 93.3% for endoscopy, respectively. Both US and endoscopy exhibited good diagnostic accuracy for NPC with area under the curve (AUC) values of 0.929 and 0.938, respectively. However, this difference was not significant (Z = 0.36, P = 0.72). CONCLUSION:US is a useful tool for the detection of tumors in endoscopically suspicious nasopharynx tissues, and also for the detection of subclinical tumors in endoscopically normal nasopharynx tissues. |
| first_indexed | 2024-04-12T04:04:54Z |
| format | Article |
| id | doaj.art-57ed54cebc6f426cb0243f9d94f42125 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-12T04:04:54Z |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-57ed54cebc6f426cb0243f9d94f421252022-12-22T03:48:37ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0193e9041210.1371/journal.pone.0090412The diagnostic accuracy of ultrasonography versus endoscopy for primary nasopharyngeal carcinoma.Yong GaoJun-Jie LiuShang-Yong ZhuXiang YiOBJECTIVE:To compare the accuracy of ultrasonography (US) with the current clinical standard of endoscopy for a diagnosis of nasopharyngeal carcinoma (NPC). METHODS:A total of 150 patients suspected of having NPC underwent US and endoscopy. A diagnosis was obtained from an endoscopic biopsy collected from each suspected tumor and was compared with a biopsy obtained from a normal nasopharynx. The diagnostic accuracy of US and endoscopy for NPC was evaluated using receiver operating curve (ROC) analysis performed by MedCalc Software. RESULTS:The sensitivity, specificity, and accuracy of US versus endoscopy for this cohort were 90.1%, 84.8%, and 87.3% for US, and 88.7%, 97.5%, and 93.3% for endoscopy, respectively. Both US and endoscopy exhibited good diagnostic accuracy for NPC with area under the curve (AUC) values of 0.929 and 0.938, respectively. However, this difference was not significant (Z = 0.36, P = 0.72). CONCLUSION:US is a useful tool for the detection of tumors in endoscopically suspicious nasopharynx tissues, and also for the detection of subclinical tumors in endoscopically normal nasopharynx tissues.http://europepmc.org/articles/PMC3940890?pdf=render |
| spellingShingle | Yong Gao Jun-Jie Liu Shang-Yong Zhu Xiang Yi The diagnostic accuracy of ultrasonography versus endoscopy for primary nasopharyngeal carcinoma. PLoS ONE |
| title | The diagnostic accuracy of ultrasonography versus endoscopy for primary nasopharyngeal carcinoma. |
| title_full | The diagnostic accuracy of ultrasonography versus endoscopy for primary nasopharyngeal carcinoma. |
| title_fullStr | The diagnostic accuracy of ultrasonography versus endoscopy for primary nasopharyngeal carcinoma. |
| title_full_unstemmed | The diagnostic accuracy of ultrasonography versus endoscopy for primary nasopharyngeal carcinoma. |
| title_short | The diagnostic accuracy of ultrasonography versus endoscopy for primary nasopharyngeal carcinoma. |
| title_sort | diagnostic accuracy of ultrasonography versus endoscopy for primary nasopharyngeal carcinoma |
| url | http://europepmc.org/articles/PMC3940890?pdf=render |
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