The Prevalence, Antibiotic Resistance Pattern, and Associated Factors of Bacterial Vaginosis Among Women of the Reproductive Age Group from Felege Hiwot Referral Hospital, Ethiopia
Abebaw Bitew, Abeba Mengist, Habtamu Belew, Yibeltal Aschale, Alemayehu Reta Department of Medical Laboratory Science, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, EthiopiaCorrespondence: Abebaw Bitew Tel +251 912 477495Email abebawbit05@gmail.comBackground: Bacter...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2021-07-01
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| Series: | Infection and Drug Resistance |
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| Online Access: | https://www.dovepress.com/the-prevalence-antibiotic-resistance-pattern-and-associated-factors-of-peer-reviewed-fulltext-article-IDR |
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| author | Bitew A Mengist A Belew H Aschale Y Reta A |
| author_facet | Bitew A Mengist A Belew H Aschale Y Reta A |
| author_sort | Bitew A |
| collection | DOAJ |
| description | Abebaw Bitew, Abeba Mengist, Habtamu Belew, Yibeltal Aschale, Alemayehu Reta Department of Medical Laboratory Science, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, EthiopiaCorrespondence: Abebaw Bitew Tel +251 912 477495Email abebawbit05@gmail.comBackground: Bacterial vaginosis is an infection of the vagina, which results due to change in the normal balance of vaginal bacteria. The aim of this study was to assess the magnitude and determinants of bacterial vaginosis among women of reproductive age group from Felege Hiwot Referral Hospital.Materials and Methods: A cross-sectional study was conducted among women during the reproductive period at Felege Hiwot Referral Hospital from September 1, 2019 to October 2020. About 413 vaginal swab samples were collected and examined using the Nugent scoring system and culture. Data were analyzed by SPSS version 25. The odds ratio (OR) was used as a measure of the strength of association and reported with 95% confidence intervals. P-value ≤ 0.05 was considered to be statistically significant. Bivariate and multivariate logistic regression models were used to identify possible associated factors with bacteria causing bacterial vaginosis.Results: The overall prevalence of bacteria causing bacterial vaginosis was 39.5%. The predominant bacteria were S. aureus (25.4%), G. vaginalis (22.7%), S. agalactiae (14.1%), and E. coli (13.5%). S. aureus was resistant to erythromycin (69.8%) and trimethoprim/sulfamethoxazole (53.5%); despite this, it was susceptible to ciprofloxacillin (93%), gentamycin (93%), and cefoxitin (90.7%). On the other hand, E. coli was resistant to trimethoprim/sulfamethoxazole (91.3%) and ceftriaxone (63.6%), but was susceptible to ciprofloxacillin (95.5%) and gentamycin (93%).Conclusion: The high prevalence of bacterial vaginosis was significantly associated with the pH level of the vagina (≥ 4.5), participant age ≤ 20, pregnancy, and history of HIV infection. Therefore, early identification of factors leading to bacterial overgrowth on the vagina is very important to protect maternal and child morbidity and mortality.Keywords: aerobic bacteria, bacterial vaginosis, Gardnerella vaginalis, Lactobacillus |
| first_indexed | 2024-12-17T02:34:41Z |
| format | Article |
| id | doaj.art-57edfe535131434ca2966c9c5404e493 |
| institution | Directory Open Access Journal |
| issn | 1178-6973 |
| language | English |
| last_indexed | 2024-12-17T02:34:41Z |
| publishDate | 2021-07-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Infection and Drug Resistance |
| spelling | doaj.art-57edfe535131434ca2966c9c5404e4932022-12-21T22:06:53ZengDove Medical PressInfection and Drug Resistance1178-69732021-07-01Volume 142685269666926The Prevalence, Antibiotic Resistance Pattern, and Associated Factors of Bacterial Vaginosis Among Women of the Reproductive Age Group from Felege Hiwot Referral Hospital, EthiopiaBitew AMengist ABelew HAschale YReta AAbebaw Bitew, Abeba Mengist, Habtamu Belew, Yibeltal Aschale, Alemayehu Reta Department of Medical Laboratory Science, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, EthiopiaCorrespondence: Abebaw Bitew Tel +251 912 477495Email abebawbit05@gmail.comBackground: Bacterial vaginosis is an infection of the vagina, which results due to change in the normal balance of vaginal bacteria. The aim of this study was to assess the magnitude and determinants of bacterial vaginosis among women of reproductive age group from Felege Hiwot Referral Hospital.Materials and Methods: A cross-sectional study was conducted among women during the reproductive period at Felege Hiwot Referral Hospital from September 1, 2019 to October 2020. About 413 vaginal swab samples were collected and examined using the Nugent scoring system and culture. Data were analyzed by SPSS version 25. The odds ratio (OR) was used as a measure of the strength of association and reported with 95% confidence intervals. P-value ≤ 0.05 was considered to be statistically significant. Bivariate and multivariate logistic regression models were used to identify possible associated factors with bacteria causing bacterial vaginosis.Results: The overall prevalence of bacteria causing bacterial vaginosis was 39.5%. The predominant bacteria were S. aureus (25.4%), G. vaginalis (22.7%), S. agalactiae (14.1%), and E. coli (13.5%). S. aureus was resistant to erythromycin (69.8%) and trimethoprim/sulfamethoxazole (53.5%); despite this, it was susceptible to ciprofloxacillin (93%), gentamycin (93%), and cefoxitin (90.7%). On the other hand, E. coli was resistant to trimethoprim/sulfamethoxazole (91.3%) and ceftriaxone (63.6%), but was susceptible to ciprofloxacillin (95.5%) and gentamycin (93%).Conclusion: The high prevalence of bacterial vaginosis was significantly associated with the pH level of the vagina (≥ 4.5), participant age ≤ 20, pregnancy, and history of HIV infection. Therefore, early identification of factors leading to bacterial overgrowth on the vagina is very important to protect maternal and child morbidity and mortality.Keywords: aerobic bacteria, bacterial vaginosis, Gardnerella vaginalis, Lactobacillushttps://www.dovepress.com/the-prevalence-antibiotic-resistance-pattern-and-associated-factors-of-peer-reviewed-fulltext-article-IDRaerobic bacteriabacterial vaginosisgardnerella vaginalislactobacillus |
| spellingShingle | Bitew A Mengist A Belew H Aschale Y Reta A The Prevalence, Antibiotic Resistance Pattern, and Associated Factors of Bacterial Vaginosis Among Women of the Reproductive Age Group from Felege Hiwot Referral Hospital, Ethiopia Infection and Drug Resistance aerobic bacteria bacterial vaginosis gardnerella vaginalis lactobacillus |
| title | The Prevalence, Antibiotic Resistance Pattern, and Associated Factors of Bacterial Vaginosis Among Women of the Reproductive Age Group from Felege Hiwot Referral Hospital, Ethiopia |
| title_full | The Prevalence, Antibiotic Resistance Pattern, and Associated Factors of Bacterial Vaginosis Among Women of the Reproductive Age Group from Felege Hiwot Referral Hospital, Ethiopia |
| title_fullStr | The Prevalence, Antibiotic Resistance Pattern, and Associated Factors of Bacterial Vaginosis Among Women of the Reproductive Age Group from Felege Hiwot Referral Hospital, Ethiopia |
| title_full_unstemmed | The Prevalence, Antibiotic Resistance Pattern, and Associated Factors of Bacterial Vaginosis Among Women of the Reproductive Age Group from Felege Hiwot Referral Hospital, Ethiopia |
| title_short | The Prevalence, Antibiotic Resistance Pattern, and Associated Factors of Bacterial Vaginosis Among Women of the Reproductive Age Group from Felege Hiwot Referral Hospital, Ethiopia |
| title_sort | prevalence antibiotic resistance pattern and associated factors of bacterial vaginosis among women of the reproductive age group from felege hiwot referral hospital ethiopia |
| topic | aerobic bacteria bacterial vaginosis gardnerella vaginalis lactobacillus |
| url | https://www.dovepress.com/the-prevalence-antibiotic-resistance-pattern-and-associated-factors-of-peer-reviewed-fulltext-article-IDR |
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