Bufei Yishen formula protects the airway epithelial barrier and ameliorates COPD by enhancing autophagy through the Sirt1/AMPK/Foxo3 signaling pathway

Bufei Yishen formula protects the airway epithelial barrier and ameliorates COPD by enhancing autophagy through the Sirt1/AMPK/Foxo3 signaling pathway

Abstract Object Bufei Yishen formula (BYF), a traditional Chinese medicine alleviates COPD symptoms and suppresses airway epithelial inflammation. In this study, we determined whether BYF protects the airway epithelial barrier from destruction in COPD rats. Methods The protective effects of BYF on t...

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Bibliographic Details
Main Authors: Lidan Jia, Xuefang Liu, Xinguang Liu, Qingzhou Guan, Yange Tian, Jiansheng Li, Peng Zhao
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Chinese Medicine
Subjects:
Chronic obstructive pulmonary disease
Bufei Yishen formula
Airway epithelial barrier
SIRT1/AMPK/FOXO3 signals
Autophagy
Online Access:https://doi.org/10.1186/s13020-024-00905-1

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